First and last authorship publications of the Medical Immunology Campus Erlangen members

2016

September

Willebrand R., Voehringer D.: Regulation of eosinophil development and survival. Curr. Opin. Hematol. 2016 Sep 26 [Epub ahead of print] PMID: 27673511

Andreev K., Trufa D., Siegemund R., Rieker R., Hartmann A., Schmidt J., Sirbu H., Finotto S.: Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma. Br. J. Cancer 2016 Sep 22 [Epub ahead of print] PMID: 27657338

Putz F., Putz T., Goerig N., Knippen S., Gryc T., Eyüpoglu I., Rössler K., Semrau S., Lettmaier S., Fietkau R.: Improved survival for elderly married glioblastoma patients : Better treatment delivery, less toxicity, and fewer disease complications. Strahlenther Onkol 2016 Sep 14 [Epub ahead of print] PMID: 27628965

Popp V., Gerlach K., Mott S., Turowska A., Garn H., Atreya R., Lehr H., Ho I., Renz H., Weigmann B., Neurath M.: Rectal Delivery of a DNAzyme That Specifically Blocks the Transcription Factor GATA3 Reduces Colitis in Mice. Gastroenterology 2016 Sep 14 [Epub ahead of print] PMID: 27639807

López-Posadas R., Neurath M., Atreya I.: Molecular pathways driving disease-specific alterations of intestinal epithelial cells. Cell. Mol. Life Sci. 2016 Sep 13 [Epub ahead of print] PMID: 27624395

Linker R., Wendt G.: Cardiac Safety Profile of First Dose of Fingolimod for Relapsing-Remitting Multiple Sclerosis in Real-World Settings: Data from a German Prospective Multi-Center Observational Study. Neurol Ther 2016 Sep 13 [Epub ahead of print] PMID: 27624575

Kraus C., Hoyer J., Vasileiou G., Wunderle M., Lux M., Fasching P., Krumbiegel M., Uebe S., Reuter M., Beckmann M., Reis A.: Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2. Int. J. Cancer 2016 Sep 12 [Epub ahead of print] PMID: 27616075

Mummert C., Hofmann C., Hückelhoven A., Bergmann S., Mueller-Schmucker S., Harrer E., Dörrie J., Schaft N., Harrer T.: T-cell receptor transfer for boosting HIV-1-specific T-cell immunity in HIV-1-infected patients. AIDS 2016;30:2149-58 PMID: 27258398

Xu W., Wang J., Yuan T., Li Y., Yang H., Liu Y., Zhao Y., Herrmann M.: Interactions between canonical Wnt signaling pathway and MAPK pathway regulate differentiation, maturation and function of dendritic cells. Cell. Immunol. 2016 Sep 08 [Epub ahead of print] PMID: 27641635

Zilker C., Kozlova D., Sokolova V., Yan H., Epple M., Überla K., Temchura V.: Nanoparticle-based B-cell targeting vaccines: Tailoring of humoral immune responses by functionalization with different TLR-ligands. Nanomedicine 2016 Sep 02 [Epub ahead of print] PMID: 27593489

Qorraj M., Bruns H., Böttcher M., Weigand L., Saul D., Mackensen A., Jitschin R., Mougiakakos D.: The PD-1/PD-L1 axis contributes to immune metabolic dysfunctions of monocytes in chronic lymphocytic leukemia. Leukemia 2016 Sep 02 [Epub ahead of print] PMID: 27479178

August

Seliger B., Jasinski-Bergner S., Quandt D., Stoehr C., Bukur J., Wach S., Legal W., Taubert H., Wullich B., Hartmann A.: HLA-E expression and its clinical relevance in human renal cell carcinoma. Oncotarget 2016 Aug 31 [Epub ahead of print] PMID: 27589686

Figueiredo C., Simon D., Englbrecht M., Haschka J., Kleyer A., Bayat S., Hueber A., Pereira R., Rech J., Schett G.: Quantification and Impact of Secondary Osteoarthritis in Patients With Anti-Citrullinated Protein Antibody-Positive Rheumatoid Arthritis. Arthritis Rheumatol 2016;68:2114-21 PMID: 27059535

Reick C., Ellrichmann G., Tsai T., Lee D., Wiese S., Gold R., Saft C., Linker R.: Expression of brain-derived neurotrophic factor in astrocytes - Beneficial effects of glatiramer acetate in the R6/2 and YAC128 mouse models of Huntington's disease. Exp. Neurol. 2016;285:12-23 PMID: 27587303

Nebel N., Maschauer S., Kuwert T., Hocke C., Prante O.: In Vitro and In Vivo Characterization of Selected Fluorine-18 Labeled Radioligands for PET Imaging of the Dopamine D3 Receptor. Molecules 2016;21: PMID: 27589704

He G., Günther C., Kremer A., Thonn V., Amann K., Poremba C., Neurath M., Wirtz S., Becker C.: PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury. Gut 2016 Aug 26 [Epub ahead of print] PMID: 27566130

Ettle B., Kuhbandner K., Jörg S., Hoffmann A., Winkler J., Linker R.: α-Synuclein deficiency promotes neuroinflammation by increasing Th1 cell-mediated immune responses. J Neuroinflammation 2016;13:201 PMID: 27565429

Milbradt J., Hutterer C., Bahsi H., Wagner S., Sonntag E., Horn A., Kaufer B., Mori Y., Sticht H., Fossen T., Marschall M.: The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress. PLoS Pathog. 2016;12:e1005825 PMID: 27556400

Atreya I., Neurath M.: Microbiota: relevant player in thiopurine metabolisation? Gut 2016 Aug 24 [Epub ahead of print] PMID: 27558925

Hilpert C., Sitte S., Matthies A., Voehringer D.: Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection. J. Immunol. 2016;197:2780-6 PMID: 27549169

Hildner K., Punkenburg E., Abendroth B., Neurath M.: Immunopathogenesis of IBD: Batf as a Key Driver of Disease Activity. Dig Dis 2016;34:40-7 PMID: 27548324

Zundler S., Schillinger D., Fischer A., Atreya R., López-Posadas R., Watson A., Neufert C., Atreya I., Neurath M.: Blockade of αEβ7 integrin suppresses accumulation of CD8+ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo. Gut 2016 Aug 19 [Epub ahead of print] PMID: 27543429

Steingruber M., Kraut A., Socher E., Sticht H., Reichel A., Stamminger T., Amin B., Couté Y., Hutterer C., Marschall M.: Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins. Viruses 2016;8: PMID: 27548200

Mielenz D., Gunn-Moore F.: Physiological and pathophysiological functions of Swiprosin-1/EFhd2 in the nervous system. Biochem. J. 2016;473:2429-37 PMID: 27515255

Yang H., Biermann M., Brauner J., Liu Y., Zhao Y., Herrmann M.: New Insights into Neutrophil Extracellular Traps: Mechanisms of Formation and Role in Inflammation. Front Immunol 2016;7:302 PMID: 27570525

Hahn A., Großkopf A., Jungnickl D., Scholz B., Ensser A.: Viral FGARAT Homolog ORF75 of Rhesus Monkey Rhadinovirus Effects Proteasomal Degradation of the ND10 Components SP100 and PML. J. Virol. 2016;90:8013-28 PMID: 27356898

Schmidt B., Hupfer M., Saltybaeva N., Kolditz D., Kalender W.: Dose Optimization for Computed Tomography Localizer Radiographs for Low-Dose Lung Computed Tomography Examinations. Invest Radiol 2016 Aug 11 [Epub ahead of print] PMID: 27518213

Mihai S., Albert H., Ludwig R., Iwata H., Björck L., Collin M., Nimmerjahn F.: In vivo enzymatic modulation of IgG antibodies prevents immune complex-dependent skin injury. Exp. Dermatol. 2016 Aug 11 [Epub ahead of print] PMID: 27512946

Kirchberger M., Hauschild A., Schuler G., Heinzerling L.: Combined low-dose ipilimumab and pembrolizumab after sequential ipilimumab and pembrolizumab failure in advanced melanoma. Eur. J. Cancer 2016;65:182-4 PMID: 27501507

Zhang H., Pluhackova K., Jiang Z., Böckmann R.: Binding Characteristics of Sphingosine-1-Phosphate to ApoM hints to Assisted Release Mechanism via the ApoM Calyx-Opening. Sci Rep 2016;6:30655 PMID: 27476912

July

Ackermann J., Hofheinz K., Zaiss M., Krönke G.: The double-edged role of 12/15-lipoxygenase during inflammation and immunity. Biochim. Biophys. Acta 2016 Jul 30 [Epub ahead of print] PMID: 27480217

Danzer C., Koller A., Baier J., Arnold H., Giessler C., Opoka R., Schmidt S., Willers M., Mihai S., Parsch H., Wirtz S., Daniel C., Reinhold A., Engelmann S., Kliche S., Bogdan C., Hoebe K., Mattner J.: A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice. Eur. J. Immunol. 2016;46:2121-36 PMID: 27349342

Britzen-Laurent N., Herrmann C., Naschberger E., Croner R., Stürzl M.: Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases. World J. Gastroenterol. 2016;22:6434-43 PMID: 27605879

Özgör L., Brandl C., Shock A., Nitschke L.: Epratuzumab modulates B-cell signaling without affecting B-cell numbers or B-cell functions in a mouse model with humanized CD22. Eur. J. Immunol. 2016;46:2260-72 PMID: 27352780

Löhr S., Uebe S., Behrens F., Böhm B., Köhm M., Traupe H., Oji V., Burkhardt H., Reis A., Hüffmeier U.: Association analysis of psoriasis vulgaris and psoriatic arthritis with loss-of-function mutations in IL36RN in German patients. Br. J. Dermatol. 2016;175:639-41 PMID: 27038307

Gmeiner B., Maser A., Utikal T., Götzinger S., Sandoghdar V.: Spectroscopy and microscopy of single molecules in nanoscopic channels: spectral behavior vs. confinement depth. Phys Chem Chem Phys 2016;18:19588-94 PMID: 27327379

Bressan E., Touska F., Vetter I., Kistner K., Kichko T., Teixeira N., Picolo G., Cury Y., Lewis R., Fischer M., Zimmermann K., Reeh P.: Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia. Pain 2016 Jul 18 [Epub ahead of print] PMID: 27434506

Sandoval A., Eichler S., Madathil S., Reeves P., Fahmy K., Böckmann R.: The Molecular Switching Mechanism at the Conserved D(E)RY Motif in Class-A GPCRs. Biophys. J. 2016;111:79-89 PMID: 27410736

Bertz S., Wach S., Taubert H., Merten R., Krause F., Schick S., Ott O., Weigert E., Dworak O., Rödel C., Fietkau R., Wullich B., Keck B., Hartmann A.: Micropapillary morphology is an indicator of poor prognosis in patients with urothelial carcinoma treated with transurethral resection and radiochemotherapy. Virchows Arch. 2016;469:339-44 PMID: 27392930

Auoragh A., Strnad V., Ott O., Beckmann M., Fietkau R.: Re-irradiation of the chest wall for local breast cancer recurrence : Results of salvage brachytherapy with hyperthermia. Strahlenther Onkol 2016;192:617-23 PMID: 27381751

Schmitt H., Sell S., Koch J., Seefried M., Sonnewald S., Daniel C., Winkler T., Nitschke L.: Siglec-H protects from virus-triggered severe systemic autoimmunity. J. Exp. Med. 2016;213:1627-44 PMID: 27377589

Hahn J., Knopf J., Maueröder C., Kienhöfer D., Leppkes M., Herrmann M.: Neutrophils and neutrophil extracellular traps orchestrate initiation and resolution of inflammation. Clin. Exp. Rheumatol. 0;34:6-8 PMID: 27586795

June

Kienhöfer D., Boeltz S., Hoffmann M.: Reactive oxygen homeostasis - the balance for preventing autoimmunity. Lupus 2016;25:943-54 PMID: 27252273

Knippertz I., Deinzer A., Dörrie J., Schaft N., Nettelbeck D., Steinkasserer A.: Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation. J Immunol Res 2016;2016:6078473 PMID: 27446966

Knippertz I., Deinzer A., Dörrie J., Schaft N., Nettelbeck D., Steinkasserer A.: Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation. J Immunol Res 2016;2016:6078473 PMID: 27446966

Atreya R., Neurath M.: Predicting Therapeutic Response by in vivo Molecular Imaging in Inflammatory Bowel Diseases. Dig Dis 2016;34:552-7 PMID: 27333283

Schäfer W., Eckart R., Schmid B., Cagköylü H., Hof K., Muller Y., Amin B., Lührmann A.: Nuclear trafficking of the anti-apoptotic Coxiella burnetii effector protein AnkG requires binding to p32 and Importin-α1. Cell. Microbiol. 2016 Jun 21 [Epub ahead of print] PMID: 27328359

Figueiredo C., Bang H., Cobra J., Englbrecht M., Hueber A., Haschka J., Manger B., Kleyer A., Reiser M., Finzel S., Tony H., Kleinert S., Wendler J., Schuch F., Ronneberger M., Feuchtenberger M., Fleck M., Manger K., Ochs W., Schmitt-Haendle M., Lorenz H., Nuesslein H., Alten R., Henes J., Krueger K., Rech J., Schett G.: Antimodified protein antibody response pattern influences the risk for disease relapse in patients with rheumatoid arthritis tapering disease modifying antirheumatic drugs. Ann. Rheum. Dis. 2016 Jun 20 [Epub ahead of print] PMID: 27323772

Deloch L., Derer A., Hartmann J., Frey B., Fietkau R., Gaipl U.: Modern Radiotherapy Concepts and the Impact of Radiation on Immune Activation. Front Oncol 2016;6:141 PMID: 27379203

Lai X., Wolkenhauer O., Vera J.: Understanding microRNA-mediated gene regulatory networks through mathematical modelling. Nucleic Acids Res. 2016;44:6019-35 PMID: 27317695

Scherer M., Stamminger T.: Emerging Role of PML Nuclear Bodies in Innate Immune Signaling. J. Virol. 2016;90:5850-4 PMID: 27053550

Henrich F., Singer K., Poller K., Bernhardt L., Strobl C., Limm K., Ritter A., Gottfried E., Völkl S., Jacobs B., Peter K., Mougiakakos D., Dettmer K., Oefner P., Bosserhoff A., Kreutz M., Aigner M., Mackensen A.: Suppressive effects of tumor cell-derived 5'-deoxy-5'-methylthioadenosine on human T cells. Oncoimmunology 2016;5:e1184802 PMID: 27622058

Goerig N., Frey B., Korn K., Fleckenstein B., Überla K., Schmidt M., Dörfler A., Engelhorn T., Eyüpoglu I., Rühle P., Putz F., Semrau S., Gaipl U., Fietkau R.: Frequent occurrence of therapeutically reversible CMV-associated encephalopathy during radiotherapy of the brain. Neuro-oncology 2016 Jun 10 [Epub ahead of print] PMID: 27286796

Linker R., Haghikia A.: Dimethyl fumarate in multiple sclerosis: latest developments, evidence and place in therapy. Ther Adv Chronic Dis 2016;7:198-207 PMID: 27433310

Seibold J., Strnad V., Fietkau R.: Organ-sparing treatment of penile cancer with interstitial pulsed-dose-rate brachytherapy. Strahlenther Onkol 2016;192:467-72 PMID: 27276876

Krumbholz M., Hellberg J., Steif B., Bäuerle T., Gillmann C., Fritscher T., Agaimy A., Frey B., Juengert J., Wardelmann E., Hartmann W., Juergens H., Dirksen U., Metzler M.: Genomic EWSR1 Fusion Sequence as Highly Sensitive and Dynamic Plasma Tumor Marker in Ewing Sarcoma. Clin. Cancer Res. 2016;22:4356-65 PMID: 27283964

Chen Z., Andreev D., Oeser K., Krljanac B., Hueber A., Kleyer A., Voehringer D., Schett G., Bozec A.: Th2 and eosinophil responses suppress inflammatory arthritis. Nat Commun 2016;7:11596 PMID: 27273006

Schwartz C., Eberle J., Hoyler T., Diefenbach A., Lechmann M., Voehringer D.: Opposing functions of thymic stromal lymphopoietin-responsive basophils and dendritic cells in a mouse model of atopic dermatitis. J. Allergy Clin. Immunol. 2016 Jun 04 [Epub ahead of print] PMID: 27372565

Uslu U., Schuler G., Dörrie J., Schaft N.: Combining a chimeric antigen receptor and a conventional T-cell receptor to generate T cells expressing two additional receptors (TETARs) for a multi-hit immunotherapy of melanoma. Exp. Dermatol. 2016 Jun 01 [Epub ahead of print] PMID: 27246630

Huber A., Kallerup R., Korsholm K., Franzyk H., Lepenies B., Christensen D., Foged C., Lang R.: Trehalose diester glycolipids are superior to the monoesters in binding to Mincle, activation of macrophages in vitro and adjuvant activity in vivo. Innate Immun 2016;22:405-18 PMID: 27252171

May

Goerig N., Semrau S., Frey B., Korn K., Fleckenstein B., Überla K., Dörfler A., Putz F., Gaipl U., Fietkau R.: Clinically significant CMV (re)activation during or after radiotherapy/chemotherapy of the brain : Correlation with neurological deterioration and improvement upon antiviral treatment. Strahlenther Onkol 2016;192:489-97 PMID: 27245820

Atreya R., Bloom S., Scaldaferri F., Gerardi V., Admyre C., Karlsson Å., Knittel T., Kowalski J., Lukas M., Löfberg R., Nancey S., Petryka R., Rydzewska G., Schnabel R., Seidler U., Neurath M., Hawkey C.: Clinical Effects of a Topically Applied Toll-like Receptor 9 Agonist in Active Moderate-to-Severe Ulcerative Colitis. J Crohns Colitis 2016 May 20 [Epub ahead of print] PMID: 27208386

Kleyer A., Krieter M., Oliveira I., Faustini F., Simon D., Kaemmerer N., Cavalcante A., Tabosa T., Rech J., Hueber A., Schett G.: High prevalence of tenosynovial inflammation before onset of rheumatoid arthritis and its link to progression to RA-A combined MRI/CT study. Semin. Arthritis Rheum. 2016;46:143-50 PMID: 27342772

Mahapatro M., Foersch S., Hefele M., He G., Giner-Ventura E., Mchedlidze T., Kindermann M., Vetrano S., Danese S., Günther C., Neurath M., Wirtz S., Becker C.: Programming of Intestinal Epithelial Differentiation by IL-33 Derived from Pericryptal Fibroblasts in Response to Systemic Infection. Cell Rep 2016;15:1743-56 PMID: 27184849

Chen G., Luo Y., Eriksson D., Meng X., Qian C., Bäuerle T., Chen X., Schett G., Bozec A.: High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6. Oncotarget 2016;7:26653-69 PMID: 27049717

April

Gandesiri M., Chakilam S., Ivanovska J., Benderska N., Ocker M., Di Fazio P., Feoktistova M., Gali-Muhtasib H., Rave-Fränk M., Prante O., Christiansen H., Leverkus M., Hartmann A., Schneider-Stock R.: Erratum to: DAPK plays an important role in panobinostat-induced autophagy and commits cells to apoptosis under autophagy deficient conditions. Apoptosis 2016;21:671-4 PMID: 26960313

Buchholz B., Schley G., Eckardt K.: The impact of hypoxia on nephrogenesis. Curr. Opin. Nephrol. Hypertens. 2016;25:180-6 PMID: 27023836

Santos G., Nikolov S., Lai X., Eberhardt M., Dreyer F., Paul S., Schuler G., Vera J.: Model-based genotype-phenotype mapping used to investigate gene signatures of immune sensitivity and resistance in melanoma micrometastasis. Sci Rep 2016;6:24967 PMID: 27113331

Eberle J., Voehringer D.: Role of basophils in protective immunity to parasitic infections. Semin Immunopathol 2016;38:605-13 PMID: 27116557

Palumbo-Zerr K., Soare A., Zerr P., Liebl A., Mancuso R., Tomcik M., Sumova B., Dees C., Chen C., Wohlfahrt T., Mallano T., Distler A., Ramming A., Gelse K., Mihai C., Distler O., Schett G., Distler J.: Composition of TWIST1 dimers regulates fibroblast activation and tissue fibrosis. Ann. Rheum. Dis. 2016 Apr 25 [Epub ahead of print] PMID: 27113414

Friedrich M., Setz C., Hahn F., Matthaei A., Fraedrich K., Rauch P., Henklein P., Traxdorf M., Fossen T., Schubert U.: Glutamic Acid Residues in HIV-1 p6 Regulate Virus Budding and Membrane Association of Gag. Viruses 2016;8:117 PMID: 27120610

Atreya I., Diall A., Dvorsky R., Atreya R., Henninger C., Grün M., Hofmann U., Schaeffeler E., López-Posadas R., Daehn I., Zenker S., Döbrönti M., Neufert C., Billmeier U., Zundler S., Fritz G., Schwab M., Neurath M.: Designer Thiopurine-analogues for Optimised Immunosuppression in Inflammatory Bowel Diseases. J Crohns Colitis 2016;10:1132-43 PMID: 27112707

Schleicher U., Paduch K., Debus A., Obermeyer S., König T., Kling J., Ribechini E., Dudziak D., Mougiakakos D., Murray P., Ostuni R., Körner H., Bogdan C.: TNF-Mediated Restriction of Arginase 1 Expression in Myeloid Cells Triggers Type 2 NO Synthase Activity at the Site of Infection. Cell Rep 2016;15:1062-75 PMID: 27117406

Völkl S., Rensing-Ehl A., Allgäuer A., Schreiner E., Lorenz M., Rohr J., Klemann C., Fuchs I., Schuster V., von Bueren A., Naumann-Bartsch N., Gambineri E., Siepermann K., Kobbe R., Nathrath M., Arkwright P., Miano M., Stachel K., Metzler M., Schwarz K., Kremer A., Speckmann C., Ehl S., Mackensen A.: Hyperactive mTOR pathway promotes lymphoproliferation and abnormal differentiation in autoimmune lymphoproliferative syndrome. Blood 2016;128:227-38 PMID: 27099149

Otte M., Mahler V., Kerpes A., Pabst O., Voehringer D.: Persistence of the IgE repertoire in birch pollen allergy. J. Allergy Clin. Immunol. 2016;137:1884-1887.e8 PMID: 27001158

Haghikia A., Jörg S., Duscha A., Berg J., Manzel A., Waschbisch A., Hammer A., Lee D., May C., Wilck N., Balogh A., Ostermann A., Schebb N., Akkad D., Grohme D., Kleinewietfeld M., Kempa S., Thöne J., Demir S., Müller D., Gold R., Linker R.: Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. Immunity 2016;44:951-3 PMID: 27096322

Pluhackova K., Kirsch S., Han J., Sun L., Jiang Z., Unruh T., Böckmann R.: A Critical Comparison of Biomembrane Force Fields: Structure and Dynamics of Model DMPC, POPC, and POPE Bilayers. J Phys Chem B 2016;120:3888-903 PMID: 27035634

Zimmer L., Goldinger S., Hofmann L., Loquai C., Ugurel S., Thomas I., Schmidgen M., Gutzmer R., Utikal J., Göppner D., Hassel J., Meier F., Tietze J., Forschner A., Weishaupt C., Leverkus M., Wahl R., Dietrich U., Garbe C., Kirchberger M., Eigentler T., Berking C., Gesierich A., Krackhardt A., Schadendorf D., Schuler G., Dummer R., Heinzerling L.: Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy. Eur. J. Cancer 2016;60:210-25 PMID: 27084345

Hofmann L., Forschner A., Loquai C., Goldinger S., Zimmer L., Ugurel S., Schmidgen M., Gutzmer R., Utikal J., Göppner D., Hassel J., Meier F., Tietze J., Thomas I., Weishaupt C., Leverkus M., Wahl R., Dietrich U., Garbe C., Kirchberger M., Eigentler T., Berking C., Gesierich A., Krackhardt A., Schadendorf D., Schuler G., Dummer R., Heinzerling L.: Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy. Eur. J. Cancer 2016;60:190-209 PMID: 27085692

Nimmerjahn F.: Immunomodulation of immunothrombocytopenia. Semin. Hematol. 2016;53:S10-2 PMID: 27312154

March

Roessler A., Hupfer M., Kolditz D., Jost G., Pietsch H., Kalender W.: High Atomic Number Contrast Media Offer Potential for Radiation Dose Reduction in Contrast-Enhanced Computed Tomography. Invest Radiol 2016;51:249-54 PMID: 26606552

Neurath M.: Confocal laser endomicroscopy for functional barrier imaging in Crohn's disease. Endoscopy 2016;48:319-20 PMID: 27022840

Lehmann C., Heger L., Heidkamp G., Baranska A., Lühr J., Hoffmann A., Dudziak D.: Direct Delivery of Antigens to Dendritic Cells via Antibodies Specific for Endocytic Receptors as a Promising Strategy for Future Therapies. Vaccines (Basel) 2016;4: PMID: 27043640

Amich J., Dümig M., O'Keeffe G., Binder J., Doyle S., Beilhack A., Krappmann S.: Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant. Infect. Immun. 2016;84:917-29 PMID: 26787716

Doerfler W.: Beware of manipulations on the genome: epigenetic destabilization through (foreign) DNA insertions. Epigenomics 2016;8:587-91 PMID: 26997469

Mchedlidze T., Kindermann M., Neves A., Voehringer D., Neurath M., Wirtz S.: IL-27 suppresses type 2 immune responses in vivo via direct effects on group 2 innate lymphoid cells. Mucosal Immunol 2016 Mar 16 [Epub ahead of print] PMID: 26982595

Krzyzak L., Seitz C., Urbat A., Hutzler S., Ostalecki C., Gläsner J., Hiergeist A., Gessner A., Winkler T., Steinkasserer A., Nitschke L.: CD83 Modulates B Cell Activation and Germinal Center Responses. J. Immunol. 2016;196:3581-94 PMID: 26983787

Koch S., Graser A., Mirzakhani H., Zimmermann T., Melichar V., Wölfel M., Croteau-Chonka D., Raby B., Weiss S., Finotto S.: Increased expression of nuclear factor of activated T cells 1 drives IL-9-mediated allergic asthma. J. Allergy Clin. Immunol. 2016;137:1898-1902.e7 PMID: 26993036

Thöne J., Linker R.: Laquinimod in the treatment of multiple sclerosis: a review of the data so far. Drug Des Devel Ther 2016;10:1111-8 PMID: 27042003

Leppkes M., Maueröder C., Hirth S., Nowecki S., Günther C., Billmeier U., Paulus S., Biermann M., Munoz L., Hoffmann M., Wildner D., Croxford A., Waisman A., Mowen K., Jenne D., Krenn V., Mayerle J., Lerch M., Schett G., Wirtz S., Neurath M., Herrmann M., Becker C.: Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis. Nat Commun 2016;7:10973 PMID: 26964500

Jörg S., Kissel J., Manzel A., Kleinewietfeld M., Haghikia A., Gold R., Müller D., Linker R.: High salt drives Th17 responses in experimental autoimmune encephalomyelitis without impacting myeloid dendritic cells. Exp. Neurol. 2016;279:212-22 PMID: 26976739

Braun M., Qorraj M., Büttner M., Klein F., Saul D., Aigner M., Huber W., Mackensen A., Jitschin R., Mougiakakos D.: CXCL12 promotes glycolytic reprogramming in acute myeloid leukemia cells via the CXCR4/mTOR axis. Leukemia 2016;30:1788-92 PMID: 26952837

Nimmerjahn F.: Translating Inhibitory Fc Receptor Biology into Novel Therapeutic Approaches. J. Clin. Immunol. 2016;36:83-7 PMID: 26957094

Sopel N., Graser A., Mousset S., Finotto S.: The transcription factor BATF modulates cytokine-mediated responses in T cells. Cytokine Growth Factor Rev. 2016;30:39-45 PMID: 26970726

Neurath M., Finotto S.: IL-9 signaling as key driver of chronic inflammation in mucosal immunity. Cytokine Growth Factor Rev. 2016;29:93-9 PMID: 26976761

February

Radtke D., Lacher S., Szumilas N., Sandrock L., Ackermann J., Nitschke L., Zinser E.: Grb2 Is Important for T Cell Development, Th Cell Differentiation, and Induction of Experimental Autoimmune Encephalomyelitis. J. Immunol. 2016;196:2995-3005 PMID: 26921310

Birge R., Boeltz S., Kumar S., Carlson J., Wanderley J., Calianese D., Barcinski M., Brekken R., Huang X., Hutchins J., Freimark B., Empig C., Mercer J., Schroit A., Schett G., Herrmann M.: Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer. Cell Death Differ. 2016;23:962-78 PMID: 26915293

Floege J., Amann K.: Primary glomerulonephritides. Lancet 2016;387:2036-48 PMID: 26921911

Lankes K., Hundorfean G., Harrer T., Pommer A., Agaimy A., Angelovska I., Tajmir-Riahi A., Göhl J., Schuler G., Neurath M., Hohenberger W., Heinzerling L.: Anti-TNF-refractory colitis after checkpoint inhibitor therapy: Possible role of CMV-mediated immunopathogenesis. Oncoimmunology 2016;5:e1128611 PMID: 27471608

Sun L., Bertelshofer F., Greiner G., Böckmann R.: Characteristics of Sucrose Transport through the Sucrose-Specific Porin ScrY Studied by Molecular Dynamics Simulations. Front Bioeng Biotechnol 2016;4:9 PMID: 26913282

Lehmann W., Mossmann D., Kleemann J., Mock K., Meisinger C., Brummer T., Herr R., Brabletz S., Stemmler M., Brabletz T.: ZEB1 turns into a transcriptional activator by interacting with YAP1 in aggressive cancer types. Nat Commun 2016;7:10498 PMID: 26876920

Akkad D., Lee D., Bruch K., Haghikia A., Epplen J., Hoffjan S., Linker R.: Multiple sclerosis in families: risk factors beyond known genetic polymorphisms. Neurogenetics 2016;17:131-5 PMID: 26865406

Lin N., Distler A., Beyer C., Philipi-Schöbinger A., Breda S., Dees C., Stock M., Tomcik M., Niemeier A., Dell'Accio F., Gelse K., Mattson M., Schett G., Distler J.: Inhibition of Notch1 promotes hedgehog signalling in a HES1-dependent manner in chondrocytes and exacerbates experimental osteoarthritis. Ann. Rheum. Dis. 2016 Feb 05 [Epub ahead of print] PMID: 26851274

Han J., Pluhackova K., Bruns D., Böckmann R.: Synaptobrevin transmembrane domain determines the structure and dynamics of the SNARE motif and the linker region. Biochim. Biophys. Acta 2016;1858:855-65 PMID: 26851777

Kichko T., Pfirrmann R., Reeh P.: Taurolidine and congeners activate hTRPA1 but not hTRPV1 channels and stimulate CGRP release from mouse tracheal sensory nerves. Pharmacol Res Perspect 2016;4:e00204 PMID: 26977296

January

Martini E., Wittkopf N., Günther C., Leppkes M., Okada H., Watson A., Podstawa E., Backert I., Amann K., Neurath M., Becker C.: Loss of Survivin in Intestinal Epithelial Progenitor Cells Leads to Mitotic Catastrophe and Breakdown of Gut Immune Homeostasis. Cell Rep 2016;14:1062-73 PMID: 26832409

Schey R., Dornhoff H., Baier J., Purtak M., Opoka R., Koller A., Atreya R., Rau T., Daniel C., Amann K., Bogdan C., Mattner J.: CD101 inhibits the expansion of colitogenic T cells. Mucosal Immunol 2016;9:1205-17 PMID: 26813346

Magorivska I., Muñoz L., Janko C., Dumych T., Rech J., Schett G., Nimmerjahn F., Bilyy R., Herrmann M.: Sialylation of anti-histone immunoglobulin G autoantibodies determines their capabilities to participate in the clearance of late apoptotic cells. Clin. Exp. Immunol. 2016;184:110-7 PMID: 26618514

Haschka J., Hirschmann S., Kleyer A., Englbrecht M., Faustini F., Simon D., Figueiredo C., Schuster L., Muschitz C., Kocijan R., Resch H., Atreya R., Rech J., Neurath M., Schett G.: High-resolution Quantitative Computed Tomography Demonstrates Structural Defects in Cortical and Trabecular Bone in IBD Patients. J Crohns Colitis 2016;10:532-40 PMID: 26818661

Flentje M., Huber R., Engel-Riedel W., Andreas S., Kollmeier J., Staar S., Dickgreber N., Vaissiere N., De Almeida C., Edlich B., Fietkau R.: GILT--A randomised phase III study of oral vinorelbine and cisplatin with concomitant radiotherapy followed by either consolidation therapy with oral vinorelbine and cisplatin or best supportive care alone in stage III non-small cell lung cancer. Strahlenther Onkol 2016;192:216-22 PMID: 26809652

Groß A., Hashimoto C., Sticht H., Eichler J.: Synthetic Peptides as Protein Mimics. Front Bioeng Biotechnol 2015;3:211 PMID: 26835447

Bisle S., Klingenbeck L., Borges V., Sobotta K., Schulze-Luehrmann J., Menge C., Heydel C., Gomes J., Lührmann A.: The inhibition of the apoptosis pathway by the Coxiella burnetii effector protein CaeA requires the EK repetition motif, but is independent of survivin. Virulence 2016;7:400-12 PMID: 26760129

Werthmöller N., Frey B., Rückert M., Lotter M., Fietkau R., Gaipl U.: Combination of ionising radiation with hyperthermia increases the immunogenic potential of B16-F10 melanoma cells in vitro and in vivo. Int J Hyperthermia 2016;32:23-30 PMID: 26754406

López-Posadas R., Becker C., Günther C., Tenzer S., Amann K., Billmeier U., Atreya R., Fiorino G., Vetrano S., Danese S., Ekici A., Wirtz S., Thonn V., Watson A., Brakebusch C., Bergö M., Neurath M., Atreya I.: Rho-A prenylation and signaling link epithelial homeostasis to intestinal inflammation. J. Clin. Invest. 2016;126:611-26 PMID: 26752649

Waschbisch A., Schröder S., Schraudner D., Sammet L., Weksler B., Melms A., Pfeifenbring S., Stadelmann C., Schwab S., Linker R.: Pivotal Role for CD16+ Monocytes in Immune Surveillance of the Central Nervous System. J. Immunol. 2016;196:1558-67 PMID: 26746191

Graser A., Ekici A., Sopel N., Melichar V., Zimmermann T., Papadopoulos N., Taka S., Ferrazzi F., Vuorinen T., Finotto S.: Rhinovirus inhibits IL-17A and the downstream immune responses in allergic asthma. Mucosal Immunol 2016;9:1183-92 PMID: 26732679

2015

December

Schwabe K., Garcia M., Ubieta K., Hannemann N., Herbort B., Luther J., Noël D., Jorgensen C., Casteilla L., David J., Stock M., Herrmann M., Schett G., Bozec A.: Inhibition of Osteoarthritis by Adipose-Derived Stromal Cells Overexpressing Fra-1 in Mice. Arthritis Rheumatol 2016;68:138-51 PMID: 26361381

Kirsch S., Böckmann R.: Membrane pore formation in atomistic and coarse-grained simulations. Biochim. Biophys. Acta 2016;1858:2266-77 PMID: 26748016

Zaiss M., Harris N.: Interactions between the intestinal microbiome and helminth parasites. Parasite Immunol. 2016;38:5-11 PMID: 26345715

Nebel N., Maschauer S., Hocke C., Hübner H., Gmeiner P., Prante O.: Optimization and synthesis of an (18) F-labeled dopamine D3 receptor ligand using [(18) F]fluorophenylazocarboxylic tert-butylester. J Labelled Comp Radiopharm 2016;59:48-53 PMID: 26707848

Hoyer S., Gerer K., Pfeiffer I., Prommersberger S., Höfflin S., Jaitly T., Beltrame L., Cavalieri D., Schuler G., Vera J., Schaft N., Dörrie J.: Electroporated Antigen-Encoding mRNA Is Not a Danger Signal to Human Mature Monocyte-Derived Dendritic Cells. J Immunol Res 2015;2015:952184 PMID: 26824052

Chen X., Lee K., Eghlidi H., Götzinger S., Sandoghdar V.: Enhancing the radiative emission rate of single molecules by a plasmonic nanoantenna weakly coupled with a dielectric substrate. Opt Express 2015;23:32986-92 PMID: 26831966

Muñoz L., Bilyy R., Biermann M., Kienhöfer D., Maueröder C., Hahn J., Brauner J., Weidner D., Chen J., Scharin-Mehlmann M., Janko C., Friedrich R., Mielenz D., Dumych T., Lootsik M., Schauer C., Schett G., Hoffmann M., Zhao Y., Herrmann M.: Nanoparticles size-dependently initiate self-limiting NETosis-driven inflammation. Proc. Natl. Acad. Sci. U.S.A. 2016;113:E5856-E5865 PMID: 27647892

Jackson C., Best L., Lorenzo L., Casanova J., Wacker J., Bertz S., Agaimy A., Harrer T.: A Multiplex Kindred with Hennekam Syndrome due to Homozygosity for a CCBE1 Mutation that does not Prevent Protein Expression. J. Clin. Immunol. 2016;36:19-27 PMID: 26686525

Wittmann S., Behrendt R., Eissmann K., Volkmann B., Thomas D., Ebert T., Cribier A., Benkirane M., Hornung V., Bouzas N., Gramberg T.: Phosphorylation of murine SAMHD1 regulates its antiretroviral activity. Retrovirology 2015;12:103 PMID: 26667483

Schley G., Köberle C., Manuilova E., Rutz S., Forster C., Weyand M., Formentini I., Kientsch-Engel R., Eckardt K., Willam C.: Comparison of Plasma and Urine Biomarker Performance in Acute Kidney Injury. PLoS ONE 2015;10:e0145042 PMID: 26669323

Maxwell P., Eckardt K.: HIF prolyl hydroxylase inhibitors for the treatment of renal anaemia and beyond. Nat Rev Nephrol 2016;12:157-68 PMID: 26656456

Jacobi J., Beckmann S., Heller K., Hilgers K., Apel H., Spriewald B., Eckardt K., Amann K.: Deceased Donor Kidney Transplantation in the Eurotransplant Senior Program (ESP): A Single-Center Experience from 2008 to 2013. Ann. Transplant. 2016;21:94-104 PMID: 26864516

Schett G., Dayer J., Manger B.: Interleukin-1 function and role in rheumatic disease. Nat Rev Rheumatol 2016;12:14-24 PMID: 26656658

Muth C., Rubner Y., Semrau S., Rühle P., Frey B., Strnad A., Buslei R., Fietkau R., Gaipl U.: Primary glioblastoma multiforme tumors and recurrence : Comparative analysis of the danger signals HMGB1, HSP70, and calreticulin. Strahlenther Onkol 2016;192:146-55 PMID: 26646311

Hutterer C., Hamilton S., Steingruber M., Zeitträger I., Bahsi H., Thuma N., Naing Z., Örfi Z., Örfi L., Socher E., Sticht H., Rawlinson W., Chou S., Haupt V., Marschall M.: The chemical class of quinazoline compounds provides a core structure for the design of anticytomegaloviral kinase inhibitors. Antiviral Res. 2016;134:130-143 PMID: 27515131

Martini E., Schneider E., Neufert C., Neurath M., Becker C.: Survivin is a guardian of the intestinal stem cell niche and its expression is regulated by TGF-β. Cell Cycle 2015 Dec 07 [Epub ahead of print] PMID: 27715398

Atreya R., Billmeier U., Rath T., Mudter J., Vieth M., Neumann H., Neurath M.: First case report of exacerbated ulcerative colitis after anti-interleukin-6R salvage therapy. World J. Gastroenterol. 2015;21:12963-9 PMID: 26668517

Kao D., Danzer H., Collin M., Groß A., Eichler J., Stambuk J., Lauc G., Lux A., Nimmerjahn F.: A Monosaccharide Residue Is Sufficient to Maintain Mouse and Human IgG Subclass Activity and Directs IgG Effector Functions to Cellular Fc Receptors. Cell Rep 2015;13:2376-85 PMID: 26670049

Brandl A., Daum P., Brenner S., Schulz S., Yap D., Bösl M., Wittmann J., Schuh W., Jäck H.: The microprocessor component, DGCR8, is essential for early B-cell development in mice. Eur. J. Immunol. 2015 Dec 05 [Epub ahead of print] PMID: 27641147

Weber S., Jung S., Doerfler W.: DNA methylation and transcription in HERV (K, W, E) and LINE sequences remain unchanged upon foreign DNA insertions. Epigenomics 2016;8:157-65 PMID: 26627183

Willebrand R., Voehringer D.: IL-33-Induced Cytokine Secretion and Survival of Mouse Eosinophils Is Promoted by Autocrine GM-CSF. PLoS ONE 0;11:e0163751 PMID: 27690378

November

Schmeck B., Bertrams W., Lai X., Vera J.: Systems Medicine for Lung Diseases: Phenotypes and Precision Medicine in Cancer, Infection, and Allergy. Methods Mol. Biol. 2016;1386:119-33 PMID: 26677183

Herrmann A., Happel A., Gramberg T.: SAMHD1 in Retroviral Restriction and Innate Immune Sensing--Should We Leash the Hound? Curr. HIV Res. 2016;14:225-34 PMID: 26957197

Frey B., Derer A., Scheithauer H., Wunderlich R., Fietkau R., Gaipl U.: Cancer Cell Death-Inducing Radiotherapy: Impact on Local Tumour Control, Tumour Cell Proliferation and Induction of Systemic Anti-tumour Immunity. Adv. Exp. Med. Biol. 2016;930:151-72 PMID: 27558821

Eberhardt M., Lai X., Tomar N., Gupta S., Schmeck B., Steinkasserer A., Schuler G., Vera J.: Third-Kind Encounters in Biomedicine: Immunology Meets Mathematics and Informatics to Become Quantitative and Predictive. Methods Mol. Biol. 2016;1386:135-79 PMID: 26677184

Dreyer F., Baur A.: Biogenesis and Functions of Exosomes and Extracellular Vesicles. Methods Mol. Biol. 2016;1448:201-16 PMID: 27317183

Candeias S., Gaipl U.: The Immune System in Cancer Prevention, Development and Therapy. Anticancer Agents Med Chem 2016;16:101-7 PMID: 26299661

Weigmann B., Neurath M.: Oxazolone-Induced Colitis as a Model of Th2 Immune Responses in the Intestinal Mucosa. Methods Mol. Biol. 2016;1422:253-61 PMID: 27246039

Sasse A., Hamer S., Amich J., Binder J., Krappmann S.: Mutant characterization and in vivo conditional repression identify aromatic amino acid biosynthesis to be essential for Aspergillus fumigatus virulence. Virulence 2016;7:56-62 PMID: 26605426

Horn A., Sticht H.: Synthetic Protein Scaffolds Based on Peptide Motifs and Cognate Adaptor Domains for Improving Metabolic Productivity. Front Bioeng Biotechnol 2015;3:191 PMID: 26636078

Derer A., Frey B., Fietkau R., Gaipl U.: Immune-modulating properties of ionizing radiation: rationale for the treatment of cancer by combination radiotherapy and immune checkpoint inhibitors. Cancer Immunol. Immunother. 2016;65:779-86 PMID: 26590829

Böttcher M., Hofmann A., Bruns H., Haibach M., Loschinski R., Saul D., Mackensen A., Le Blanc K., Jitschin R., Mougiakakos D.: Mesenchymal Stromal Cells Disrupt mTOR-Signaling and Aerobic Glycolysis During T-Cell Activation. Stem Cells 2016;34:516-21 PMID: 26485560

Bertelshofer F., Sun L., Greiner G., Böckmann R.: GroPBS: Fast Solver for Implicit Electrostatics of Biomolecules. Front Bioeng Biotechnol 2015;3:186 PMID: 26636074

Scherer M., Otto V., Stump J., Klingl S., Müller R., Reuter N., Muller Y., Sticht H., Stamminger T.: Characterization of Recombinant Human Cytomegaloviruses Encoding IE1 Mutants L174P and 1-382 Reveals that Viral Targeting of PML Bodies Perturbs both Intrinsic and Innate Immune Responses. J. Virol. 2016;90:1190-205 PMID: 26559840

Graf L., Feichtinger S., Naing Z., Hutterer C., Milbradt J., Webel R., Wagner S., Scott G., Hamilton S., Rawlinson W., Stamminger T., Thomas M., Marschall M.: New insight into the phosphorylation-regulated intranuclear localization of human cytomegalovirus pUL69 mediated by cyclin-dependent kinases (CDKs) and viral CDK orthologue pUL97. J. Gen. Virol. 2016;97:144-51 PMID: 26555090

Hutterer C., Niemann I., Milbradt J., Fröhlich T., Reiter C., Kadioglu O., Bahsi H., Zeitträger I., Wagner S., Einsiedel J., Gmeiner P., Vogel N., Wandinger S., Godl K., Stamminger T., Efferth T., Tsogoeva S., Marschall M.: The broad-spectrum antiinfective drug artesunate interferes with the canonical nuclear factor kappa B (NF-κB) pathway by targeting RelA/p65. Antiviral Res. 2015;124:101-9 PMID: 26546752

Ivanovska J., Zlobec I., Forster S., Karamitopoulou E., Dawson H., Koelzer V., Agaimy A., Garreis F., Söder S., Laqua W., Lugli A., Hartmann A., Rau T., Schneider-Stock R.: DAPK loss in colon cancer tumor buds: implications for migration capacity of disseminating tumor cells. Oncotarget 2015;6:36774-88 PMID: 26405175

Turqueti-Neves A., Otte M., Schwartz C., Schmitt M., Lindner C., Pabst O., Yu P., Voehringer D.: The Extracellular Domains of IgG1 and T Cell-Derived IL-4/IL-13 Are Critical for the Polyclonal Memory IgE Response In Vivo. PLoS Biol. 2015;13:e1002290 PMID: 26523376

October

Gordan S., Biburger M., Nimmerjahn F.: bIgG time for large eaters: monocytes and macrophages as effector and target cells of antibody-mediated immune activation and repression. Immunol. Rev. 2015;268:52-65 PMID: 26497512

Krug C., Birkholz K., Paulus A., Schwenkert M., Schmidt P., Hoffmann N., Hombach A., Fey G., Abken H., Schuler G., Schuler-Thurner B., Dörrie J., Schaft N.: Stability and activity of MCSP-specific chimeric antigen receptors (CARs) depend on the scFv antigen-binding domain and the protein backbone. Cancer Immunol. Immunother. 2015;64:1623-35 PMID: 26515978

Zaiss M., Rapin A., Lebon L., Dubey L., Mosconi I., Sarter K., Piersigilli A., Menin L., Walker A., Rougemont J., Paerewijck O., Geldhof P., McCoy K., Macpherson A., Croese J., Giacomin P., Loukas A., Junt T., Marsland B., Harris N.: The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation. Immunity 2015;43:998-1010 PMID: 26522986

Hammon M., Grossmann S., Linz P., Kopp C., Dahlmann A., Garlichs C., Janka R., Cavallaro A., Luft F., Uder M., Titze J.: 23Na Magnetic Resonance Imaging of the Lower Leg of Acute Heart Failure Patients during Diuretic Treatment. PLoS ONE 2015;10:e0141336 PMID: 26501774

Hofheinz K., Schett G., Manger B.: Adult onset Still's disease associated with malignancy-Cause or coincidence? Semin. Arthritis Rheum. 2016;45:621-6 PMID: 26581485

Flügel-Koch C., Croft M., Kaufman P., Lütjen-Drecoll E.: Anteriorly located zonular fibres as a tool for fine regulation in accommodation. Ophthalmic Physiol Opt 2016;36:13-20 PMID: 26490669

Maschauer S., Gahr S., Gandesiri M., Tripal P., Schneider-Stock R., Kuwert T., Ocker M., Prante O.: In vivo monitoring of the anti-angiogenic therapeutic effect of the pan-deacetylase inhibitor panobinostat by small animal PET in a mouse model of gastrointestinal cancers. Nucl. Med. Biol. 2016;43:27-34 PMID: 26702784

Haghikia A., Jörg S., Duscha A., Berg J., Manzel A., Waschbisch A., Hammer A., Lee D., May C., Wilck N., Balogh A., Ostermann A., Schebb N., Akkad D., Grohme D., Kleinewietfeld M., Kempa S., Thöne J., Demir S., Müller D., Gold R., Linker R.: Dietary Fatty Acids Directly Impact Central Nervous System Autoimmunity via the Small Intestine. Immunity 2015;43:817-29 PMID: 26488817

Rech J., Hueber A., Finzel S., Englbrecht M., Haschka J., Manger B., Kleyer A., Reiser M., Cobra J., Figueiredo C., Tony H., Kleinert S., Wendler J., Schuch F., Ronneberger M., Feuchtenberger M., Fleck M., Manger K., Ochs W., Schmitt-Haendle M., Lorenz H., Nuesslein H., Alten R., Henes J., Krueger K., Schett G.: Prediction of disease relapses by multibiomarker disease activity and autoantibody status in patients with rheumatoid arthritis on tapering DMARD treatment. Ann. Rheum. Dis. 2016;75:1637-44 PMID: 26483255

Storcksdieck genannt Bonsmann M., Niezold T., Temchura V., Pissani F., Ehrhardt K., Brown E., Osei-Owusu N., Hannaman D., Hengel H., Ackerman M., Streeck H., Nabi G., Tenbusch M., Überla K.: Enhancing the Quality of Antibodies to HIV-1 Envelope by GagPol-Specific Th Cells. J. Immunol. 2015;195:4861-72 PMID: 26466954

Schwab I., Lux A., Nimmerjahn F.: Pathways Responsible for Human Autoantibody and Therapeutic Intravenous IgG Activity in Humanized Mice. Cell Rep 2015;13:610-20 PMID: 26456831

Derer A., Deloch L., Rubner Y., Fietkau R., Frey B., Gaipl U.: Radio-Immunotherapy-Induced Immunogenic Cancer Cells as Basis for Induction of Systemic Anti-Tumor Immune Responses - Pre-Clinical Evidence and Ongoing Clinical Applications. Front Immunol 2015;6:505 PMID: 26500646

Lee D., Steinacker P., Seubert S., Turnescu T., Melms A., Manzel A., Otto M., Linker R.: Role of glial 14-3-3 gamma protein in autoimmune demyelination. J Neuroinflammation 2015;12:187 PMID: 26438180

Walzer S., Egerer-Sieber C., Sticht H., Sevvana M., Hohl K., Milbradt J., Muller Y., Marschall M.: Crystal Structure of the Human Cytomegalovirus pUL50-pUL53 Core Nuclear Egress Complex Provides Insight into a Unique Assembly Scaffold for Virus-Host Protein Interactions. J. Biol. Chem. 2015;290:27452-8 PMID: 26432641

September

Kiesslich R., Neurath M.: Advances in detection and management of dysplasia in inflammatory bowel disease: Is endoscopic submucosal dissection ready for prime time in inflammatory bowel disease? Gastrointest. Endosc. 2015;82:739-41 PMID: 26385281

Haep L., Britzen-Laurent N., Weber T., Naschberger E., Schaefer A., Kremmer E., Foersch S., Vieth M., Scheuer W., Wirtz S., Waldner M., Stürzl M.: Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice. Inflamm. Bowel Dis. 2015;21:2360-71 PMID: 26164664

Arnold M., Fuernrohr B., Weiß K., Harre U., Wiesener M., Spriewald B.: Association of a coding polymorphism in Fc gamma receptor 2A and graft survival in re-transplant candidates. Hum. Immunol. 2015;76:759-64 PMID: 26429312

Schulze-Luehrmann J., Eckart R., Ölke M., Saftig P., Liebler-Tenorio E., Lührmann A.: LAMP proteins account for the maturation delay during the establishment of the Coxiella burnetii-containing vacuole. Cell. Microbiol. 2016;18:181-94 PMID: 26249821

Titze J., Rakova N., Kopp C., Dahlmann A., Jantsch J., Luft F.: Balancing wobbles in the body sodium. Nephrol. Dial. Transplant. 2016;31:1078-81 PMID: 26410883

Luo Y., Chen G., Hannemann N., Ipseiz N., Krönke G., Bäuerle T., Munos L., Wirtz S., Schett G., Bozec A.: Microbiota from Obese Mice Regulate Hematopoietic Stem Cell Differentiation by Altering the Bone Niche. Cell Metab. 2015;22:886-94 PMID: 26387866

Kötter B., Frey B., Winderl M., Rubner Y., Scheithauer H., Sieber R., Fietkau R., Gaipl U.: The in vitro immunogenic potential of caspase-3 proficient breast cancer cells with basal low immunogenicity is increased by hypofractionated irradiation. Radiat Oncol 2015;10:197 PMID: 26383236

Ott O., Jeremias C., Gaipl U., Frey B., Schmidt M., Fietkau R.: Radiotherapy for benign achillodynia. Long-term results of the Erlangen Dose Optimization Trial. Strahlenther Onkol 2015;191:979-84 PMID: 26369640

Neurath M.: Molecular Endoscopy and in vivo Imaging in Inflammatory Bowel Diseases. Dig Dis 2015;33:32-36 PMID: 26366988

Andreev K., Trufa I., Siegemund R., Rieker R., Hartmann A., Schmidt J., Sirbu H., Finotto S.: Impaired T-bet-pSTAT1α and perforin-mediated immune responses in the tumoral region of lung adenocarcinoma. Br. J. Cancer 2015;113:902-13 PMID: 26348446

Schneider M., Hübner S., Titze S., Schmid M., Nadal J., Schlieper G., Busch M., Baid-Agrawal S., Krane V., Wanner C., Kronenberg F., Eckardt K.: Implementation of the KDIGO guideline on lipid management requires a substantial increase in statin prescription rates. Kidney Int. 2015;88:1411-1418 PMID: 26331409

Schmitz U., Naderi-Meshkin H., Gupta S., Wolkenhauer O., Vera J.: The RNA world in the 21st century-a systems approach to finding non-coding keys to clinical questions. Brief. Bioinformatics 2016;17:380-92 PMID: 26330575

Schett G.: Apremilast in psoriatic arthritis. Clin. Exp. Rheumatol. 0;33:S98-100 PMID: 26472278

August

Benderska N., Dittrich A., Knaup S., Rau T., Neufert C., Wach S., Fahlbusch F., Rauh M., Wirtz R., Agaimy A., Srinivasan S., Mahadevan V., Rümmele P., Rapti E., Gazouli M., Hartmann A., Schneider-Stock R.: miRNA-26b Overexpression in Ulcerative Colitis-associated Carcinogenesis. Inflamm. Bowel Dis. 2015;21:2039-51 PMID: 26083618

Heilingloh C., Kummer M., Mühl-Zürbes P., Drassner C., Daniel C., Klewer M., Steinkasserer A.: L Particles Transmit Viral Proteins from Herpes Simplex Virus 1-Infected Mature Dendritic Cells to Uninfected Bystander Cells, Inducing CD83 Downmodulation. J. Virol. 2015;89:11046-55 PMID: 26311871

Kichko T., Kobal G., Reeh P.: Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx. Am. J. Physiol. Lung Cell Mol. Physiol. 2015;309:L812-20 PMID: 26472811

Podolska M., Biermann M., Maueröder C., Hahn J., Herrmann M.: Inflammatory etiopathogenesis of systemic lupus erythematosus: an update. J Inflamm Res 2015;8:161-71 PMID: 26316795

Oeser K., Maxeiner J., Symowski C., Stassen M., Voehringer D.: T cells are the critical source of IL-4/IL-13 in a mouse model of allergic asthma. Allergy 2015;70:1440-9 PMID: 26214396

Han J., Pluhackova K., Wassenaar T., Böckmann R.: Synaptobrevin Transmembrane Domain Dimerization Studied by Multiscale Molecular Dynamics Simulations. Biophys. J. 2015;109:760-71 PMID: 26287628

Hückelhoven A., Etschel J., Bergmann S., Zitzelsberger K., Mueller-Schmucker S., Harrer E., Harrer T.: Cross-Reactivity Between Influenza Matrix- and HIV-1 P17-Specific CTL-A Large Cohort Study. J. Acquir. Immune Defic. Syndr. 2015;69:528-35 PMID: 25900164

Schett G., Schauer C., Hoffmann M., Herrmann M.: Why does the gout attack stop? A roadmap for the immune pathogenesis of gout. RMD Open 2015;1:e000046 PMID: 26557370

Fürnrohr B., Rhodes B., Munoz L., Weiß K., Vyse T., Schett G.: Osteoclast Differentiation Is Impaired in a Subgroup of SLE Patients and Correlates Inversely with Mycophenolate Mofetil Treatment. Int J Mol Sci 2015;16:18825-35 PMID: 26274951

Steingruber M., Socher E., Hutterer C., Webel R., Bergbrede T., Lenac T., Sticht H., Marschall M.: The Interaction between Cyclin B1 and Cytomegalovirus Protein Kinase pUL97 is Determined by an Active Kinase Domain. Viruses 2015;7:4582-601 PMID: 26270673

Lerchl K., Rakova N., Dahlmann A., Rauh M., Goller U., Basner M., Dinges D., Beck L., Agureev A., Larina I., Baranov V., Morukov B., Eckardt K., Vassilieva G., Wabel P., Vienken J., Kirsch K., Johannes B., Krannich A., Luft F., Titze J.: Agreement between 24-hour salt ingestion and sodium excretion in a controlled environment. Hypertension 2015;66:850-7 PMID: 26259596

Hess A., Roesch J., Saake M., Sergeeva M., Hirschmann S., Neumann H., Dörfler A., Neurath M., Atreya R.: Functional Brain Imaging Reveals Rapid Blockade of Abdominal Pain Response Upon Anti-TNF Therapy in Crohn's Disease. Gastroenterology 2015;149:864-6 PMID: 26264347

July

Leppkes M., Neurath M., Herrmann M., Becker C.: Immune deficiency vs. immune excess in inflammatory bowel diseases-STAT3 as a rheo-STAT of intestinal homeostasis. J. Leukoc. Biol. 2016;99:57-66 PMID: 26232455

Koch S., Reppert S., Finotto S.: NFATc1 deletion in T lymphocytes inhibits the allergic trait in a murine model of asthma. Clin. Exp. Allergy 2015;45:1356-66 PMID: 25640055

Nimmerjahn F.: A constant threat for HIV: Fc-engineering to enhance broadly neutralizing antibody activity for immunotherapy of the acquired immunodeficiency syndrome. Eur. J. Immunol. 2015;45:2183-90 PMID: 26140474

Steinmann S., Gali-Muhtasib H., Huebner K., Al-Halabi R., Abou Merhi R., Aman P., Agaimy A., Haller F., Schneider-Stock R.: Hsp90 inhibition by AUY922 as an effective treatment strategy against myxoid liposarcoma. Cancer Lett. 2015;367:147-56 PMID: 26225840

Stump J., Sticht H.: Investigation of the dynamics of the viral immediate-early protein 1 in different conformations and oligomerization states. J. Biomol. Struct. Dyn. 2016;34:1029-41 PMID: 26104474

Fischer A., Zundler S., Atreya R., Rath T., Voskens C., Hirschmann S., López-Posadas R., Watson A., Becker C., Schuler G., Neufert C., Atreya I., Neurath M.: Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo. Gut 2016;65:1642-64 PMID: 26209553

Ostrop J., Jozefowski K., Zimmermann S., Hofmann K., Strasser E., Lepenies B., Lang R.: Contribution of MINCLE-SYK Signaling to Activation of Primary Human APCs by Mycobacterial Cord Factor and the Novel Adjuvant TDB. J. Immunol. 2015;195:2417-28 PMID: 26202982

Kafurke U., Erijman A., Aizner Y., Shifman J., Eichler J.: Synthetic peptides mimicking the binding site of human acetylcholinesterase for its inhibitor fasciculin 2. J. Pept. Sci. 2015;21:723-30 PMID: 26200472

Manger B., Hiepe F., Schneider M., Worm M., Wimmer P., Paulus E., Schwarting A.: Impact of switching from mycophenolate mofetil to enteric-coated mycophenolate sodium on gastrointestinal side effects in patients with autoimmune disease: a Phase III, open-label, single-arm, multicenter study. Clin Exp Gastroenterol 2015;8:205-13 PMID: 26229499

Biburger M., Trenkwald I., Nimmerjahn F.: Three blocks are not enough--Blocking of the murine IgG receptor FcγRIV is crucial for proper characterization of cells by FACS analysis. Eur. J. Immunol. 2015;45:2694-7 PMID: 26138319

Zimmermann R., Zingsem J., Eckstein R.: Platelet Transfusion and Hemorrhage. Dtsch Arztebl Int 2015;112:505 PMID: 26249253

Nitschke L.: Siglec-G is a B-1 cell inhibitory receptor and also controls B cell tolerance. Ann. N. Y. Acad. Sci. 2015;1362:117-21 PMID: 26194636

Mielenz D., Grötsch B., David J.: Repressing the repressor: Fra1 controls plasma cell generation. Oncotarget 2015;6:17861-2 PMID: 26257006

Ramming A., Dees C., Distler J.: From pathogenesis to therapy--Perspective on treatment strategies in fibrotic diseases. Pharmacol. Res. 2015;100:93-100 PMID: 26188266

Thomas M., Sonntag E., Müller R., Schmidt S., Zielke B., Fossen T., Stamminger T.: pUL69 of Human Cytomegalovirus Recruits the Cellular Protein Arginine Methyltransferase 6 via a Domain That Is Crucial for mRNA Export and Efficient Viral Replication. J. Virol. 2015;89:9601-15 PMID: 26178996

Höfflin S., Prommersberger S., Uslu U., Schuler G., Schmidt C., Lennerz V., Dörrie J., Schaft N.: Generation of CD8(+) T cells expressing two additional T-cell receptors (TETARs) for personalised melanoma therapy. Cancer Biol. Ther. 2015;16:1323-31 PMID: 26178065

Gupta S., Jaitly T., Schmitz U., Schuler G., Wolkenhauer O., Vera J.: Personalized cancer immunotherapy using Systems Medicine approaches. Brief. Bioinformatics 2016;17:453-67 PMID: 26174229

Niedzielska M., Raffi F., Tel J., Muench S., Jozefowski K., Alati N., Lahl K., Mages J., Billmeier U., Schiemann M., Appelt U., Wirtz S., Sparwasser T., Hochrein H., Figdor C., Keyse S., Lang R.: Selective Expression of the MAPK Phosphatase Dusp9/MKP-4 in Mouse Plasmacytoid Dendritic Cells and Regulation of IFN-β Production. J. Immunol. 2015;195:1753-62 PMID: 26170386

Krumbholz M., Bradtke J., Stachel D., Peters O., Hero B., Holter W., Slany R., Metzler M.: From initiation to eradication: the lifespan of an MLL-rearranged therapy-related paediatric AML. Bone Marrow Transplant. 2015;50:1382-4 PMID: 26146805

Hilz M., Intravooth T., Moeller S., Wang R., Lee D., Koehn J., Linker R.: Central Autonomic Dysfunction Delays Recovery of Fingolimod Induced Heart Rate Slowing. PLoS ONE 2015;10:e0132139 PMID: 26147106

Hashimoto C., Eichler J.: Turning Peptide Ligands into Small-Molecule Inhibitors of Protein-Protein Interactions. Chembiochem 2015 Jul 06 [Epub ahead of print] PMID: 26147884

Zundler S., Neurath M.: Interleukin-12: Functional activities and implications for disease. Cytokine Growth Factor Rev. 2015;26:559-68 PMID: 26182974

Hammon M., Grossmann S., Linz P., Kopp C., Dahlmann A., Janka R., Cavallaro A., Uder M., Titze J.: 3 Tesla (23)Na magnetic resonance imaging during aerobic and anaerobic exercise. Acad Radiol 2015;22:1181-90 PMID: 26152501

Zundler S., Neurath M.: Immunopathogenesis of inflammatory bowel diseases: functional role of T cells and T cell homing. Clin. Exp. Rheumatol. 0;33:S19-28 PMID: 26458165

June

Seeling M., Nimmerjahn F.: Unlocking the bone: Fcγ-receptors and antibody glycosylation are keys to connecting bone homeostasis to humoral immunity. Ann Transl Med 2015;3:163 PMID: 26261834

Paul S., Vera J.: Rough hypercuboid based supervised clustering of miRNAs. Mol Biosyst 2015;11:2068-81 PMID: 25996345

Baiter M., Schuler G., Hartmann A., Schneider-Stock R., Heinzerling L.: Pathogenetic Implications of BRAF Mutation Distribution in Stage IV Melanoma Patients. Dermatology (Basel) 2015;231:127-33 PMID: 26138035

Lin N., Chen C., Kagwiria R., Liang R., Beyer C., Distler A., Luther J., Engelke K., Schett G., Distler J.: Inactivation of autophagy ameliorates glucocorticoid-induced and ovariectomy-induced bone loss. Ann. Rheum. Dis. 2016;75:1203-10 PMID: 26113650

Berens C., Bisle S., Klingenbeck L., Lührmann A.: Applying an Inducible Expression System to Study Interference of Bacterial Virulence Factors with Intracellular Signaling. J Vis Exp 2015 Jun 25 [Epub ahead of print] PMID: 26168006

Fickentscher C., Magorivska I., Janko C., Biermann M., Bilyy R., Nalli C., Tincani A., Medeghini V., Meini A., Nimmerjahn F., Schett G., Muñoz L., Andreoli L., Herrmann M.: The Pathogenicity of Anti-β2GP1-IgG Autoantibodies Depends on Fc Glycosylation. J Immunol Res 2015;2015:638129 PMID: 26185769

Frey B., Gaipl U.: Radio-immunotherapy: the focused beam expands. Lancet Oncol. 2015;16:742-3 PMID: 26095779

Mock K., Preca B., Brummer T., Brabletz S., Stemmler M., Brabletz T.: The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors. Oncotarget 2015;6:14399-412 PMID: 25973542

Wagenknecht N., Reuter N., Scherer M., Reichel A., Müller R., Stamminger T.: Contribution of the Major ND10 Proteins PML, hDaxx and Sp100 to the Regulation of Human Cytomegalovirus Latency and Lytic Replication in the Monocytic Cell Line THP-1. Viruses 2015;7:2884-907 PMID: 26057166

Strobel J., Moellmer I., Zingsem J., Hauck-Dlimi B., Eckstein R., Strasser E.: T-cell subsets in autologous and allogeneic peripheral blood stem cell concentrates. Vox Sang. 2015;109:375-86 PMID: 26040970

May

Uslu U., Agaimy A., Hundorfean G., Harrer T., Schuler G., Heinzerling L.: Autoimmune Colitis and Subsequent CMV-induced Hepatitis After Treatment With Ipilimumab. J. Immunother. 2015;38:212-5 PMID: 25962110

Neumann H., Neurath M., Atreya R.: [Endoscopic therapies in inflammatory bowel diseases]. MMW Fortschr Med 2015;157:63-6 PMID: 26099411

Fürnrohr B., Stein M., Rhodes B., Chana P., Schett G., Vyse T., Herrmann M., Mielenz D.: Reduced Fluorescence versus Forward Scatter Time-of-Flight and Increased Peak versus Integral Fluorescence Ratios Indicate Receptor Clustering in Flow Cytometry. J. Immunol. 2015;195:377-85 PMID: 26026066

Behling J., Chan A., Zeh C., Nekesa C., Heinzerling L.: Evaluating HIV Prevention Programs: Herpes Simplex Virus Type 2 Antibodies as Biomarker for Sexual Risk Behavior in Young Adults in Resource-Poor Countries. PLoS ONE 2015;10:e0128370 PMID: 26010772

Maueröder C., Kienhöfer D., Hahn J., Schauer C., Manger B., Schett G., Herrmann M., Hoffmann M.: How neutrophil extracellular traps orchestrate the local immune response in gout. J. Mol. Med. 2015;93:727-34 PMID: 26002146

Neurath M.: Advances in imaging to allow personalized medicine in Crohn's disease. Curr Opin Pharmacol 2015;23:6-10 PMID: 26002559

Stoehr R., Taubert H., Zinnall U., Giedl J., Gaisa N., Burger M., Ruemmele P., Hurst C., Knowles M., Wullich B., Hartmann A.: Frequency of TERT Promoter Mutations in Prostate Cancer. Pathobiology 2015;82:53-7 PMID: 25997473

Mössner R., Frambach Y., Wilsmann-Theis D., Löhr S., Jacobi A., Weyergraf A., Müller M., Philipp S., Renner R., Traupe H., Burkhardt H., Kingo K., Kõks S., Uebe S., Sticherling M., Sticht H., Oji V., Hüffmeier U.: Palmoplantar Pustular Psoriasis Is Associated with Missense Variants in CARD14, but Not with Loss-of-Function Mutations in IL36RN in European Patients. J. Invest. Dermatol. 2015;135:2538-41 PMID: 25989471

Weber S., Hofmann A., Herms S., Hoffmann P., Doerfler W.: Destabilization of the human epigenome: consequences of foreign DNA insertions. Epigenomics 2015;7:745-55 PMID: 26088384

Müller J., Lunz B., Schwab I., Acs A., Nimmerjahn F., Daniel C., Nitschke L.: Siglec-G Deficiency Leads to Autoimmunity in Aging C57BL/6 Mice. J. Immunol. 2015;195:51-60 PMID: 25987743

Eckhardt J., Döbbeler M., König C., Kuczera K., Kuhnt C., Ostalecki C., Zinser E., Mak T., Steinkasserer A., Lechmann M.: Thymic stromal lymphopoietin deficiency attenuates experimental autoimmune encephalomyelitis. Clin. Exp. Immunol. 2015;181:51-64 PMID: 25753260

Werthmöller N., Frey B., Wunderlich R., Fietkau R., Gaipl U.: Modulation of radiochemoimmunotherapy-induced B16 melanoma cell death by the pan-caspase inhibitor zVAD-fmk induces anti-tumor immunity in a HMGB1-, nucleotide- and T-cell-dependent manner. Cell Death Dis 2015;6:e1761 PMID: 25973681

Taubert H., Wach S., Jung R., Pugia M., Keck B., Bertz S., Nolte E., Stoehr R., Lehmann J., Ohlmann C., Stöckle M., Wullich B., Hartmann A.: Piwil 2 expression is correlated with disease-specific and progression-free survival of chemotherapy-treated bladder cancer patients. Mol. Med. 2015;21:371-80 PMID: 25998509

Nimmerjahn F., Gordan S., Lux A.: FcγR dependent mechanisms of cytotoxic, agonistic, and neutralizing antibody activities. Trends Immunol. 2015;36:325-36 PMID: 25981969

Steinmann S., Scheibe K., Erlenbach-Wuensch K., Neufert C., Schneider-Stock R.: Death-associated protein kinase: A molecule with functional antagonistic duality and a potential role in inflammatory bowel disease (Review). Int. J. Oncol. 2015;47:5-15 PMID: 25963636

Kocijan R., Englbrecht M., Haschka J., Simon D., Kleyer A., Finzel S., Kraus S., Resch H., Muschitz C., Engelke K., Sticherling M., Rech J., Schett G.: Quantitative and Qualitative Changes of Bone in Psoriasis and Psoriatic Arthritis Patients. J. Bone Miner. Res. 2015;30:1775-83 PMID: 25827104

Kammerer F., Hammon M., Schlechtweg P., Uder M., Schwab S.: A web based cross-platform application for teleconsultation in radiology. J Telemed Telecare 2015;21:355-63 PMID: 25962651

Pasutto F., Mauri L., Popp B., Sticht H., Ekici A., Piozzi E., Bonfante A., Penco S., Schlötzer-Schrehardt U., Reis A.: Whole exome sequencing reveals a novel de novo FOXC1 mutation in a patient with unrecognized Axenfeld-Rieger syndrome and glaucoma. Gene 2015;568:76-80 PMID: 25967385

Schwartz C., Eberle J., Voehringer D.: Basophils in inflammation. Eur. J. Pharmacol. 2016;778:90-5 PMID: 25959388

April

Eckardt K., Gillespie I., Kronenberg F., Richards S., Stenvinkel P., Anker S., Wheeler D., de Francisco A., Marcelli D., Froissart M., Floege J., ARO Steering Committee: High cardiovascular event rates occur within the first weeks of starting hemodialysis. Kidney Int. 2015;88:1117-25 PMID: 25923984

Fischer M., Soller K., Sauer S., Kalucka J., Veglia G., Reeh P.: Formalin evokes calcium transients from the endoplasmatic reticulum. PLoS ONE 2015;10:e0123762 PMID: 25875358

Meidhof S., Brabletz S., Lehmann W., Preca B., Mock K., Ruh M., Schüler J., Berthold M., Weber A., Burk U., Lübbert M., Puhr M., Culig Z., Wellner U., Keck T., Bronsert P., Küsters S., Hopt U., Stemmler M., Brabletz T.: ZEB1-associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat. EMBO Mol Med 2015;7:831-47 PMID: 25872941

Frey B., Hehlgans S., Rödel F., Gaipl U.: Modulation of inflammation by low and high doses of ionizing radiation: Implications for benign and malign diseases. Cancer Lett. 2015;368:230-7 PMID: 25888451

Seeling M., Nimmerjahn F.: Releasing the brakes: targeting FcγRIIB on B cells to enhance antibody-dependent lymphoma immunotherapy. Cancer Cell 2015;27:427-8 PMID: 25873165

D'Agostino M., Iagnocco A., Aegerter P., Kleyer A., Zwerina J., Perricone C., Lorenzini R., Aschenbrenner F., Willeit J., Kiechl S., Schett G.: Does subclinical inflammation contribute to impairment of function of knee joints in aged individuals? High prevalence of ultrasound inflammatory findings. Rheumatology (Oxford) 2015;54:1622-9 PMID: 25870315

Schwartz C., Willebrand R., Huber S., Rupec R., Wu D., Locksley R., Voehringer D.: Eosinophil-specific deletion of IκBα in mice reveals a critical role of NF-κB-induced Bcl-xL for inhibition of apoptosis. Blood 2015;125:3896-904 PMID: 25862560

Huang J., Beyer C., Palumbo-Zerr K., Zhang Y., Ramming A., Distler A., Gelse K., Distler O., Schett G., Wollin L., Distler J.: Nintedanib inhibits fibroblast activation and ameliorates fibrosis in preclinical models of systemic sclerosis. Ann. Rheum. Dis. 2016;75:883-90 PMID: 25858641

Bruns H., Büttner M., Fabri M., Mougiakakos D., Bittenbring J., Hoffmann M., Beier F., Pasemann S., Jitschin R., Hofmann A., Neumann F., Daniel C., Maurberger A., Kempkes B., Amann K., Mackensen A., Gerbitz A.: Vitamin D-dependent induction of cathelicidin in human macrophages results in cytotoxicity against high-grade B cell lymphoma. Sci Transl Med 2015;7:282ra47 PMID: 25855493

Rothe T., Gruber F., Uderhardt S., Ipseiz N., Rössner S., Oskolkova O., Blüml S., Leitinger N., Bicker W., Bochkov V., Yamamoto M., Steinkasserer A., Schett G., Zinser E., Krönke G.: 12/15-Lipoxygenase-mediated enzymatic lipid oxidation regulates DC maturation and function. J. Clin. Invest. 2015;125:1944-54 PMID: 25844901

Gerlach K., McKenzie A., Neurath M., Weigmann B.: IL-9 regulates intestinal barrier function in experimental T cell-mediated colitis. Tissue Barriers 2015;3:e983777 PMID: 25838986

Punkenburg E., Vogler T., Büttner M., Amann K., Waldner M., Atreya R., Abendroth B., Mudter J., Merkel S., Gallmeier E., Rose-John S., Neurath M., Hildner K.: Batf-dependent Th17 cells critically regulate IL-23 driven colitis-associated colon cancer. Gut 2016;65:1139-50 PMID: 25838550

Kuttig J., Steiding C., Kolditz D., Hupfer M., Karolczak M., Kalender W.: Comparative investigation of the detective quantum efficiency of direct and indirect conversion detector technologies in dedicated breast CT. Phys Med 2015;31:406-13 PMID: 25841299

March

Wiendl H., Elger C., Förstl H., Hartung H., Oertel W., Reichmann H., Schwab S.: Gaps Between Aims and Achievements in Therapeutic Modification of Neuronal Damage ("Neuroprotection"). Neurotherapeutics 2015;12:449-54 PMID: 25773662

Kohlmann R., Salmen A., Chan A., Knabbe C., Diekmann J., Brockmeyer N., Skaletz-Rorowski A., Michalik C., Gold R., Überla K.: Serological evidence of increased susceptibility to varicella-zoster virus reactivation or reinfection in natalizumab-treated patients with multiple sclerosis. Mult. Scler. 2015;21:1823-32 PMID: 25828755

Harre U., Lang S., Pfeifle R., Rombouts Y., Frühbeißer S., Amara K., Bang H., Lux A., Koeleman C., Baum W., Dietel K., Gröhn F., Malmström V., Klareskog L., Krönke G., Kocijan R., Nimmerjahn F., Toes R., Herrmann M., Scherer H., Schett G.: Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss. Nat Commun 2015;6:6651 PMID: 25825024

Frobenius W., Bogdan C.: Diagnostic Value of Vaginal Discharge, Wet Mount and Vaginal pH - An Update on the Basics of Gynecologic Infectiology. Geburtshilfe Frauenheilkd 2015;75:355-366 PMID: 26028693

Linker R.: [Do new oral therapies show advantages in the basal therapy of multiple sclerosis? Con]. Nervenarzt 2015;86:492-4 PMID: 25694252

Reppert S., Zinser E., Holzinger C., Sandrock L., Koch S., Finotto S.: NFATc1 deficiency in T cells protects mice from experimental autoimmune encephalomyelitis. Eur. J. Immunol. 2015;45:1426-40 PMID: 25689841

Muñoz L., Berens C., Lauber K., Gaipl U., Herrmann M.: Apoptotic cell clearance and its role in the origin and resolution of chronic inflammation. Front Immunol 2015;6:139 PMID: 25859248

Wittkopf N., Pickert G., Billmeier U., Mahapatro M., Wirtz S., Martini E., Leppkes M., Neurath M., Becker C.: Activation of intestinal epithelial Stat3 orchestrates tissue defense during gastrointestinal infection. PLoS ONE 2015;10:e0118401 PMID: 25799189

Prommersberger S., Höfflin S., Schuler-Thurner B., Schuler G., Schaft N., Dörrie J.: A new method to monitor antigen-specific CD8+ T cells, avoiding additional target cells and the restriction to human leukocyte antigen haplotype. Gene Ther. 2015;22:516-20 PMID: 25786872

Jitschin R., Braun M., Qorraj M., Saul D., Le Blanc K., Zenz T., Mougiakakos D.: Stromal cell-mediated glycolytic switch in CLL cells involves Notch-c-Myc signaling. Blood 2015;125:3432-6 PMID: 25778534

Hofmann S., Maschauer S., Kuwert T., Beck-Sickinger A., Prante O.: Synthesis and in vitro and in vivo evaluation of an (18)F-labeled neuropeptide Y analogue for imaging of breast cancer by PET. Mol. Pharm. 2015;12:1121-30 PMID: 25748228

Porstner M., Winkelmann R., Daum P., Schmid J., Pracht K., Côrte-Real J., Schreiber S., Haftmann C., Brandl A., Mashreghi M., Gelse K., Hauke M., Wirries I., Zwick M., Roth E., Radbruch A., Wittmann J., Jäck H.: miR-148a promotes plasma cell differentiation and targets the germinal center transcription factors Mitf and Bach2. Eur. J. Immunol. 2015;45:1206-15 PMID: 25678371

Pluhackova K., Wassenaar T., Kirsch S., Böckmann R.: Spontaneous adsorption of coiled-coil model peptides K and E to a mixed lipid bilayer. J Phys Chem B 2015;119:4396-408 PMID: 25719673

Hecht M., Zimmer L., Loquai C., Weishaupt C., Gutzmer R., Schuster B., Gleisner S., Schulze B., Goldinger S., Berking C., Forschner A., Clemens P., Grabenbauer G., Müller-Brenne T., Bauch J., Eich H., Grabbe S., Schadendorf D., Schuler G., Keikavoussi P., Semrau S., Fietkau R., Distel L., Heinzerling L.: Radiosensitization by BRAF inhibitor therapy-mechanism and frequency of toxicity in melanoma patients. Ann. Oncol. 2015;26:1238-44 PMID: 25762352

Groß A., Brox R., Damm D., Tschammer N., Schmidt B., Eichler J.: Ligand selectivity of a synthetic CXCR4 mimetic peptide. Bioorg. Med. Chem. 2015;23:4050-5 PMID: 25801155

Stock M., Distler A., Distler J., Beyer C., Ruiz-Heiland G., Ipseiz N., Seeling M., Krönke G., Nimmerjahn F., Schett G.: Fc-gamma receptors are not involved in cartilage damage during experimental osteoarthritis. Osteoarthr. Cartil. 2015;23:1221-5 PMID: 25748082

Jantsch J., Schatz V., Friedrich D., Schröder A., Kopp C., Siegert I., Maronna A., Wendelborn D., Linz P., Binger K., Gebhardt M., Heinig M., Neubert P., Fischer F., Teufel S., David J., Neufert C., Cavallaro A., Rakova N., Küper C., Beck F., Neuhofer W., Muller D., Schuler G., Uder M., Bogdan C., Luft F., Titze J.: Cutaneous Na+ storage strengthens the antimicrobial barrier function of the skin and boosts macrophage-driven host defense. Cell Metab. 2015;21:493-501 PMID: 25738463

Lauber K., Herrmann M.: Tumor biology: with a little help from my dying friends. Curr. Biol. 2015;25:R198-201 PMID: 25734269

February

Erber R., Gluz O., Brünner N., Kreipe H., Pelz E., Kates R., Bartels A., Huober J., Mohrmann S., Moustafa Z., Liedtke C., Möbus V., Augustin D., Thomssen C., Jänicke F., Kiechle M., Kuhn W., Nitz U., Harbeck N., Hartmann A.: Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of metalloproteinases (TIMP-1) for response to adjuvant taxane-based chemotherapy in patients with intermediate-risk breast cancer: results from the WSG-AGO EC-Doc trial. Breast Cancer Res. Treat. 2015;150:279-88 PMID: 25721604

Stein M., Blume K., Heilingloh C., Kummer M., Biesinger B., Sticht H., Steinkasserer A.: CD83 and GRASP55 interact in human dendritic cells. Biochem. Biophys. Res. Commun. 2015;459:42-8 PMID: 25701785

Jardin C., Horn A., Sticht H.: Binding properties of SUMO-interacting motifs (SIMs) in yeast. J Mol Model 2015;21:50 PMID: 25690366

Bogdan C.: Nitric oxide synthase in innate and adaptive immunity: an update. Trends Immunol. 2015;36:161-78 PMID: 25687683

Vera J., Raatz Y., Wolkenhauer O., Kottek T., Bhattacharya A., Simon J., Kunz M.: Chk1 and Wee1 control genotoxic-stress induced G2-M arrest in melanoma cells. Cell. Signal. 2015;27:951-60 PMID: 25683911

Maschauer S., Greff C., Einsiedel J., Ott J., Tripal P., Hübner H., Gmeiner P., Prante O.: Improved radiosynthesis and preliminary in vivo evaluation of a (18)F-labeled glycopeptide-peptoid hybrid for PET imaging of neurotensin receptor 2. Bioorg. Med. Chem. 2015;23:4026-33 PMID: 25691211

Sell S., Dietz M., Schneider A., Holtappels R., Mach M., Winkler T.: Control of murine cytomegalovirus infection by γδ T cells. PLoS Pathog. 2015;11:e1004481 PMID: 25658831

Floege J., Gillespie I., Kronenberg F., Anker S., Gioni I., Richards S., Pisoni R., Robinson B., Marcelli D., Froissart M., Eckardt K.: Development and validation of a predictive mortality risk score from a European hemodialysis cohort. Kidney Int. 2015;87:996-1008 PMID: 25651366

January

Lee D., Blinzler C., Stöckl T., Engelhorn T., Buslei R., Schwab S., Linker R.: [Rheumatoid vasculitis of the central nervous system]. Nervenarzt 2015;86:202-4 PMID: 25637081

Kichko T., Niedermirtl F., Leffler A., Reeh P.: Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea. Anesth. Analg. 2015;120:467-71 PMID: 25517196

Kalden J.: [Pathogenic cells of rheumatic inflammation as the target of modern therapies]. Z Rheumatol 2015;74:8-13 PMID: 25676124

Bogdan C., Steinkasserer A.: Myeloid cells and the microenvironment, microorganisms and metabolism. Immunobiology 2015;220:iii PMID: 25499734

Rath T., Billmeier U., Waldner M., Atreya R., Neurath M.: From physiology to disease and targeted therapy: interleukin-6 in inflammation and inflammation-associated carcinogenesis. Arch. Toxicol. 2015;89:541-54 PMID: 25632846

Berg S., Kaschka I., Utz K., Huhn K., Lämmer A., Lämmer R., Waschbisch A., Kloska S., Lee D., Doerfler A., Linker R.: Baseline magnetic resonance imaging of the optic nerve provides limited predictive information on short-term recovery after acute optic neuritis. PLoS ONE 2015;10:e0113961 PMID: 25635863

Groß A., Rödel K., Kneidl B., Donhauser N., Mössl M., Lump E., Münch J., Schmidt B., Eichler J.: Enhancement and induction of HIV-1 infection through an assembled peptide derived from the CD4 binding site of gp120. Chembiochem 2015;16:446-54 PMID: 25639621

Stoll A., Bergmann S., Mummert C., Mueller-Schmucker S., Spriewald B., Harrer E., Harrer T.: Identification of HLA-C restricted, HIV-1-specific CTL epitopes by peptide induced upregulation of HLA-C expression. J. Immunol. Methods 2015;418:9-18 PMID: 25633660

Hofmeister L., Perisic S., Titze J.: Tissue sodium storage: evidence for kidney-like extrarenal countercurrent systems? Pflugers Arch. 2015;467:551-8 PMID: 25600900

Tomcik M., Palumbo-Zerr K., Zerr P., Sumova B., Avouac J., Dees C., Distler A., Becvar R., Distler O., Schett G., Senolt L., Distler J.: Tribbles homologue 3 stimulates canonical TGF-β signalling to regulate fibroblast activation and tissue fibrosis. Ann. Rheum. Dis. 2016;75:609-16 PMID: 25603829

Rauscher V., Englbrecht M., van der Heijde D., Schett G., Hueber A.: High degree of nonadherence to disease-modifying antirheumatic drugs in patients with rheumatoid arthritis. J. Rheumatol. 2015;42:386-90 PMID: 25593229

Koch S., Finotto S.: Role of Interferon-λ in Allergic Asthma. J Innate Immun 2015;7:224-30 PMID: 25592858

Mallano T., Palumbo-Zerr K., Zerr P., Ramming A., Zeller B., Beyer C., Dees C., Huang J., Hai T., Distler O., Schett G., Distler J.: Activating transcription factor 3 regulates canonical TGFβ signalling in systemic sclerosis. Ann. Rheum. Dis. 2016;75:586-92 PMID: 25589515

Palumbo-Zerr K., Zerr P., Distler A., Fliehr J., Mancuso R., Huang J., Mielenz D., Tomcik M., Fürnrohr B., Scholtysek C., Dees C., Beyer C., Krönke G., Metzger D., Distler O., Schett G., Distler J.: Orphan nuclear receptor NR4A1 regulates transforming growth factor-β signaling and fibrosis. Nat. Med. 2015;21:150-8 PMID: 25581517

Lux A., Nimmerjahn F.: No need for constant help: human IgG2 antibodies have an autonomous agonistic activity for immunotherapy of cancer. Cancer Cell 2015;27:10-1 PMID: 25584890

Strnad V., Lotter M., Kreppner S., Fietkau R.: Reirradiation for recurrent head and neck cancer with salvage interstitial pulsed-dose-rate brachytherapy: Long-term results. Strahlenther Onkol 2015;191:495-500 PMID: 25575981

Amin A., Bajbouj K., Koch A., Gandesiri M., Schneider-Stock R.: Defective autophagosome formation in p53-null colorectal cancer reinforces crocin-induced apoptosis. Int J Mol Sci 2015;16:1544-61 PMID: 25584615

2014

December

Fischer J., Hueber A., Wilson S., Galm M., Baum W., Kitson C., Auer J., Lorenz S., Moelleken J., Bader M., Tissot A., Tan S., Seeber S., Schett G.: Combined inhibition of tumor necrosis factor α and interleukin-17 as a therapeutic opportunity in rheumatoid arthritis: development and characterization of a novel bispecific antibody. Arthritis Rheumatol 2015;67:51-62 PMID: 25303306

Titze J.: A different view on sodium balance. Curr. Opin. Nephrol. Hypertens. 2015;24:14-20 PMID: 25470013

Semrau S., Haderlein M., Schmidt D., Lell M., Wolf W., Waldfahrer F., Uder M., Iro H., Kuwert T., Fietkau R.: Single-cycle induction chemotherapy followed by chemoradiotherapy or surgery in patients with head and neck cancer: what are the best predictors of remission and prognosis? Cancer 2015;121:1214-22 PMID: 25537381

Kienhöfer D., Hahn J., Schubert I., Reinwald C., Ipseiz N., Lang S., Borràs È., Amann K., Sjöwall C., Barron A., Hueber A., Agerberth B., Schett G., Hoffmann M.: No evidence of pathogenic involvement of cathelicidins in patient cohorts and mouse models of lupus and arthritis. PLoS ONE 2014;9:e115474 PMID: 25535966

Kahle T., Volkmann B., Eissmann K., Herrmann A., Schmitt S., Wittmann S., Merkel L., Reuter N., Stamminger T., Gramberg T.: TRIM19/PML Restricts HIV Infection in a Cell Type-Dependent Manner. Viruses 2015;8: PMID: 26703718

Bach C., Tomova E., Goldmann K., Weisbach V., Roesler W., Mackensen A., Winkler J., Spriewald B.: Monitoring of hematopoietic chimerism by real-time quantitative PCR of micro insertions/deletions in samples with low DNA quantities. Transfus Med Hemother 2015;42:38-45 PMID: 25960714

Bergen T., Wittenberg T.: Stitching and Surface Reconstruction From Endoscopic Image Sequences: A Review of Applications and Methods. IEEE J Biomed Health Inform 2016;20:304-21 PMID: 25532214

Balabko L., Andreev K., Burmann N., Schubert M., Mathews M., Trufa D., Reppert S., Rau T., Schicht M., Sirbu H., Hartmann A., Finotto S.: Increased expression of the Th17-IL-6R/pSTAT3/BATF/RorγT-axis in the tumoural region of adenocarcinoma as compared to squamous cell carcinoma of the lung. Sci Rep 2014;4:7396 PMID: 25491772

Krappmann S.: Lightning up the worm: How to probe fungal virulence in an alternative mini-host by bioluminescence. Virulence 2015;6:727-9 PMID: 26537579

Ipseiz N., Scholtysek C., Culemann S., Krönke G.: Adopted orphans as regulators of inflammation, immunity and skeletal homeostasis. Swiss Med Wkly 2014;144:w14055 PMID: 25474159

Atreya R., Neurath M.: IBD pathogenesis in 2014: Molecular pathways controlling barrier function in IBD. Nat Rev Gastroenterol Hepatol 2015;12:67-8 PMID: 25446731

Neumann H., Kudo S., Kiesslich R., Neurath M.: Advanced colonoscopic imaging using endocytoscopy. Dig Endosc 2015;27:232-8 PMID: 25311804

November

Schwab I., Nimmerjahn F.: Role of sialylation in the anti-inflammatory activity of intravenous immunoglobulin - F(ab')₂ versus Fc sialylation. Clin. Exp. Immunol. 2014;178:97-9 PMID: 25546778

Becker C., Neurath M., Wirtz S.: The Intestinal Microbiota in Inflammatory Bowel Disease. ILAR J 2015;56:192-204 PMID: 26323629

Schey R., Danzer C., Mattner J.: Perturbations of mucosal homeostasis through interactions of intestinal microbes with myeloid cells. Immunobiology 2015;220:227-35 PMID: 25466587

Scherer M., Klingl S., Sevvana M., Otto V., Schilling E., Stump J., Müller R., Reuter N., Sticht H., Muller Y., Stamminger T.: Crystal structure of cytomegalovirus IE1 protein reveals targeting of TRIM family member PML via coiled-coil interactions. PLoS Pathog. 2014;10:e1004512 PMID: 25412268

Faez S., Türschmann P., Haakh H., Götzinger S., Sandoghdar V.: Coherent interaction of light and single molecules in a dielectric nanoguide. Phys. Rev. Lett. 2014;113:213601 PMID: 25479493

Schwartz C., Turqueti-Neves A., Hartmann S., Yu P., Nimmerjahn F., Voehringer D.: Basophil-mediated protection against gastrointestinal helminths requires IgE-induced cytokine secretion. Proc. Natl. Acad. Sci. U.S.A. 2014;111:E5169-77 PMID: 25404305

Lee D., Heidecke H., Schröder A., Paul F., Wachter R., Hoffmann R., Ellrichmann G., Dragun D., Waschbisch A., Stegbauer J., Klotz P., Gold R., Dechend R., Müller D., Saft C., Linker R.: Increase of angiotensin II type 1 receptor auto-antibodies in Huntington's disease. Mol Neurodegener 2014;9:49 PMID: 25398321

Lubgan D., Ziegaus A., Semrau S., Lambrecht U., Lettmaier S., Fietkau R.: Effective local control of vertebral metastases by simultaneous integrated boost radiotherapy: preliminary results. Strahlenther Onkol 2015;191:264-71 PMID: 25395089

Steiding C., Kolditz D., Kalender W.: Comparison of methods for acceptance and constancy testing in dental cone-beam computed tomography. Rofo 2015;187:283-90 PMID: 25389669

Benderska N., Ivanovska J., Rau T., Schulze-Luehrmann J., Mohan S., Chakilam S., Gandesiri M., Ziesché E., Fischer T., Söder S., Agaimy A., Distel L., Sticht H., Mahadevan V., Schneider-Stock R.: DAPK-HSF1 interaction as a positive-feedback mechanism stimulating TNF-induced apoptosis in colorectal cancer cells. J. Cell. Sci. 2014;127:5273-87 PMID: 25380824

Krammer R., Heinzerling L.: Therapy preferences in melanoma treatment--willingness to pay and preference of quality versus length of life of patients, physicians and healthy controls. PLoS ONE 2014;9:e111237 PMID: 25369124

October

Wiesmann V., Franz D., Held C., Münzenmayer C., Palmisano R., Wittenberg T.: Review of free software tools for image analysis of fluorescence cell micrographs. J Microsc 2015;257:39-53 PMID: 25359577

Baier J., Mattner J.: Mechanisms of autoimmune liver disease. Discov Med 2014;18:255-63 PMID: 25425466

Avouac J., Palumbo-Zerr K., Ruzehaji N., Tomcik M., Zerr P., Dees C., Distler A., Beyer C., Schneider H., Distler O., Schett G., Allanore Y., Distler J.: The nuclear receptor constitutive androstane receptor/NR1I3 enhances the profibrotic effects of transforming growth factor β and contributes to the development of experimental dermal fibrosis. Arthritis Rheumatol 2014;66:3140-50 PMID: 25155144

Atreya R., Neurath M.: Novel imaging modalities for immune cell monitoring in the intestine. Curr. Opin. Gastroenterol. 2014;30:553-8 PMID: 25197780

Hoyer S., Prommersberger S., Pfeiffer I., Schuler-Thurner B., Schuler G., Dörrie J., Schaft N.: Concurrent interaction of DCs with CD4(+) and CD8(+) T cells improves secondary CTL expansion: It takes three to tango. Eur. J. Immunol. 2014;44:3543-59 PMID: 25211552

Oeser K., Schwartz C., Voehringer D.: Conditional IL-4/IL-13-deficient mice reveal a critical role of innate immune cells for protective immunity against gastrointestinal helminths. Mucosal Immunol 2015;8:672-82 PMID: 25336167

Burk S., Erdmann M., Weiss D., Eckstein R., Strasser E.: Buffy coat volume reduction for optimization of leucapheresis harvests produced by the autoMNC program. Vox Sang. 2015;108:89-95 PMID: 25334002

Wiegers A., Sticht H., Winkler T., Britt W., Mach M.: Identification of a neutralizing epitope within antigenic domain 5 of glycoprotein B of human cytomegalovirus. J. Virol. 2015;89:361-72 PMID: 25320309

Haubner R., Maschauer S., Einsiedel J., Eder I., Rangger C., Gmeiner P., Virgolini I., Prante O.: H-CRRETAWAC-OH, a lead structure for the development of radiotracer targeting integrin α5β1? Biomed Res Int 2014;2014:243185 PMID: 25374888

Dörrie J., Krug C., Hofmann C., Müller I., Wellner V., Knippertz I., Schierer S., Thomas S., Zipperer E., Printz D., Fritsch G., Schuler G., Schaft N., Geyeregger R.: Human adenovirus-specific γ/δ and CD8+ T cells generated by T-cell receptor transfection to treat adenovirus infection after allogeneic stem cell transplantation. PLoS ONE 2014;9:e109944 PMID: 25289687

Kalender W., Saltybaeva N., Kolditz D., Hupfer M., Beister M., Schmidt B.: Generating and using patient-specific whole-body models for organ dose estimates in CT with increased accuracy: feasibility and validation. Phys Med 2014;30:925-33 PMID: 25288527

Hahn F., Setz C., Friedrich M., Rauch P., Solbak S., Frøystein N., Henklein P., Votteler J., Fossen T., Schubert U.: Mutation of the highly conserved Ser-40 of the HIV-1 p6 gag protein to Phe causes the formation of a hydrophobic patch, enhances membrane association, and polyubiquitination of Gag. Viruses 2014;6:3738-65 PMID: 25279819

September

Titze S., Schmid M., Köttgen A., Busch M., Floege J., Wanner C., Kronenberg F., Eckardt K., GCKD study investigators: Disease burden and risk profile in referred patients with moderate chronic kidney disease: composition of the German Chronic Kidney Disease (GCKD) cohort. Nephrol. Dial. Transplant. 2015;30:441-51 PMID: 25271006

Steininger P., Zimmermann R., Eckstein R., Strasser E.: Possible reasons for variable leukapheresis collection outcomes with automated apheresis systems. Transfusion 2014;54:2584-5 PMID: 25302738

Winkler T., Waisman A.: With a little help from my old T cell: memory follicular T helper cells driving autoimmunity? Eur. J. Immunol. 2014;44:2869-71 PMID: 25216178

Hüffmeier U., Mössner R.: Complex role of TNF variants in psoriatic arthritis and treatment response to anti-TNF therapy: evidence and concepts. J. Invest. Dermatol. 2014;134:2483-5 PMID: 25219647

Cumming P., Skaper D., Kuwert T., Maschauer S., Prante O.: Detection of monoamine oxidase a in brain of living rats with [18F]fluoroethyl-harmol PET. Synapse 2015;69:57-9 PMID: 25229748

Rößler A., Wenkel E., Althoff F., Kalender W.: The influence of patient positioning in breast CT on breast tissue coverage and patient comfort. Rofo 2015;187:115-22 PMID: 25243528

Rößler A., Wenkel E., Althoff F., Kalender W.: The Influence of Patient Positioning in Breast CT on Breast Tissue Coverage and Patient Comfort. Rofo 2015;36:115-22 PMID: 25912329

Pfeiffer I., Hoyer S., Gerer K., Voll R., Knippertz I., Gückel E., Schuler G., Schaft N., Dörrie J.: Triggering of NF-κB in cytokine-matured human DCs generates superior DCs for T-cell priming in cancer immunotherapy. Eur. J. Immunol. 2014;44:3413-28 PMID: 25100611

Brachs S., Turqueti-Neves A., Stein M., Reimer D., Brachvogel B., Bösl M., Winkler T., Voehringer D., Jäck H., Mielenz D.: Swiprosin-1/EFhd2 limits germinal center responses and humoral type 2 immunity. Eur. J. Immunol. 2014;44:3206-19 PMID: 25092375

Lück F., Kolditz D., Hupfer M., Steiding C., Kalender W.: Experimental validation of a single shaped filter approach for CT using variable source-to-filter distance for examination of arbitrary object diameters. Phys Med Biol 2014;59:5691-706 PMID: 25198916

Olsen P., Ruiz C., Lussier D., Le B., Angel N., Smith M., Hwang C., Khatib R., Jenkins J., Adams K., Getcher J., Tham F., Chen Z., Wilson E., Eichler J.: Synthesis, characterization, and antitumor activity of unusual pseudo five coordinate gold(III) complexes: distinct cytotoxic mechanism or expensive ligand delivery systems? J. Inorg. Biochem. 2014;141:121-31 PMID: 25243390

Schett G., Bozec A.: Removing the bone brake. Cell Metab. 2014;20:394-5 PMID: 25185946

Zerr P., Palumbo-Zerr K., Huang J., Tomcik M., Sumova B., Distler O., Schett G., Distler J.: Sirt1 regulates canonical TGF-β signalling to control fibroblast activation and tissue fibrosis. Ann. Rheum. Dis. 2016;75:226-33 PMID: 25180292

Hartmann A., Schmidt-Habel A., Löhberg L., Zajitschek J., Englbrecht M., Eichner S., Schuler G.: Treatment of vitiligo using targeted UVB-Intense Pulsed Light (IPL)- phototherapy: evaluation of variables affecting therapeutic success. Eur J Dermatol 0;24:551-9 PMID: 25445089

August

Kraus C., Rau T., Lux P., Erlenbach-Wünsch K., Löhr S., Krumbiegel M., Thiel C., Stöhr R., Agaimy A., Croner R., Stürzl M., Hohenberger W., Hartmann A., Reis A.: Comprehensive screening for mutations associated with colorectal cancer in unselected cases reveals penetrant and nonpenetrant mutations. Int. J. Cancer 2015;136:E559-68 PMID: 25142776

Schwartz C., Oeser K., Prazeres da Costa C., Layland L., Voehringer D.: T cell-derived IL-4/IL-13 protects mice against fatal Schistosoma mansoni infection independently of basophils. J. Immunol. 2014;193:3590-9 PMID: 25172500

El-Baba C., Mahadevan V., Fahlbusch F., Mohan S S., Rau T., Gali-Muhtasib H., Schneider-Stock R.: Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer. Mol. Cancer 2014;13:201 PMID: 25174975

Visco C., Finotto S.: Hepatitis C virus and diffuse large B-cell lymphoma: Pathogenesis, behavior and treatment. World J. Gastroenterol. 2014;20:11054-61 PMID: 25170194

Steiner S., Daniel C., Fischer A., Atreya I., Hirschmann S., Waldner M., Neumann H., Neurath M., Atreya R., Weigmann B.: Cyclosporine A regulates pro-inflammatory cytokine production in ulcerative colitis. Arch. Immunol. Ther. Exp. (Warsz.) 2015;63:53-63 PMID: 25155925

Schoenen H., Huber A., Sonda N., Zimmermann S., Jantsch J., Lepenies B., Bronte V., Lang R.: Differential control of Mincle-dependent cord factor recognition and macrophage responses by the transcription factors C/EBPβ and HIF1α. J. Immunol. 2014;193:3664-75 PMID: 25156364

Temchura V., Kalinin S., Nabi G., Tippler B., Niezold T., Uberla K.: Divergence of primary cognate B- and T-cell proliferative responses to subcutaneous and intravenous immunization with virus-like particles. Viruses 2014;6:3334-47 PMID: 25153345

Scheithauer H., Belka C., Lauber K., Gaipl U.: Immunological aspects of radiotherapy. Radiat Oncol 2014;9:185 PMID: 25142149

Manger B., Schett G.: Paraneoplastic syndromes in rheumatology. Nat Rev Rheumatol 2014;10:662-70 PMID: 25136782

Purohit P., Perez-Branguli F., Prots I., Borger E., Gunn-Moore F., Welzel O., Loy K., Wenzel E., Grömer T., Brachs S., Holzer M., Buslei R., Fritsch K., Regensburger M., Böhm K., Winner B., Mielenz D.: The Ca2+ sensor protein swiprosin-1/EFhd2 is present in neurites and involved in kinesin-mediated transport in neurons. PLoS ONE 2014;9:e103976 PMID: 25133820

Hecht C., Englbrecht M., Rech J., Schmidt S., Araujo E., Engelke K., Finzel S., Schett G.: Additive effect of anti-citrullinated protein antibodies and rheumatoid factor on bone erosions in patients with RA. Ann. Rheum. Dis. 2015;74:2151-6 PMID: 25115448

Übel C., Graser A., Koch S., Rieker R., Lehr H., Müller M., Finotto S.: Role of Tyk-2 in Th9 and Th17 cells in allergic asthma. Sci Rep 2014;4:5865 PMID: 25109392

Derer A., Groetsch B., Harre U., Böhm C., Towne J., Schett G., Frey S., Hueber A.: Blockade of IL-36 receptor signaling does not prevent from TNF-induced arthritis. PLoS ONE 2014;9:e101954 PMID: 25111378

Kreiser S., Eckhardt J., Kuhnt C., Stein M., Krzyzak L., Seitz C., Tucher C., Knippertz I., Becker C., Günther C., Steinkasserer A., Lechmann M.: Murine CD83-positive T cells mediate suppressor functions in vitro and in vivo. Immunobiology 2015;220:270-9 PMID: 25151500

Bolduan S., Reif T., Schindler M., Schubert U.: HIV-1 Vpu mediated downregulation of CD155 requires alanine residues 10, 14 and 18 of the transmembrane domain. Virology 2014;464:375-84 PMID: 25113908

Semrau S., Zettl H., Hildebrandt G., Klautke G., Fietkau R.: Older patients with inoperable non-small cell lung cancer: long-term survival after concurrent chemoradiotherapy. Strahlenther Onkol 2014;190:1125-32 PMID: 25098688

Dahlmann A., Dörfelt K., Eicher F., Linz P., Kopp C., Mössinger I., Horn S., Büschges-Seraphin B., Wabel P., Hammon M., Cavallaro A., Eckardt K., Kotanko P., Levin N., Johannes B., Uder M., Luft F., Müller D., Titze J.: Magnetic resonance-determined sodium removal from tissue stores in hemodialysis patients. Kidney Int. 2015;87:434-41 PMID: 25100048

July

Prante O., Haubner R., Riss P., Neumaier B.: Recent trends in pharmaceutical radiochemistry for molecular PET imaging. Biomed Res Int 2014;2014:890540 PMID: 25328892

Mohr C., Kalmer M., Gross C., Mann M., Sterz K., Kieser A., Fleckenstein B., Kress A.: The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration. Cell Commun. Signal 2014;12:46 PMID: 25105941

June

Günther C., Buchen B., He G., Hornef M., Torow N., Neumann H., Wittkopf N., Martini E., Basic M., Bleich A., Watson A., Neurath M., Becker C.: Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways. Gut 2015;64:601-10 PMID: 25379949

2013

November

Schwartz C., Voehringer D.: Identification of murine basophils by flow cytometry and histology. Methods Mol. Biol. 2014;1192:229-37 PMID: 25149496

Daeron M., Nimmerjahn F.: High amounts of specific antibodies are produced upon antigen stimulation during adaptive immune responses. Preface. Curr. Top. Microbiol. Immunol. 2014;382:v - xi PMID: 25299006

Böhm S., Kao D., Nimmerjahn F.: Sweet and sour: the role of glycosylation for the anti-inflammatory activity of immunoglobulin G. Curr. Top. Microbiol. Immunol. 2014;382:393-417 PMID: 25116110

Weigmann B.: Induction of colitis in mice (T-cell transfer model). Methods Mol. Biol. 2014;1193:143-51 PMID: 25151004

Biburger M., Lux A., Nimmerjahn F.: How immunoglobulin G antibodies kill target cells: revisiting an old paradigm. Adv. Immunol. 2014;124:67-94 PMID: 25175773

Scesnaite A., Jarmalaite S., Mueller M., Agaimy A., Zenk J., Hartmann A., Iro H., Peters B., Schwarz S., Schneider-Stock R.: Prognostic value of O-6-methylguanine-DNA methyltransferase loss in salivary gland carcinomas. Head Neck 2014;36:1258-67 PMID: 25201059